Long-term clinical outcome for patients poisoned by the fungal nephrotoxin orellanine

BMC Nephrology

Table 1 Demographic data of the Cortinarius intoxicated patient cohort

						Cont on dialysis		GFR	GFR Year	Age at intox	Admission Year				Crea	Alat	Alp	Bil	Urea	Asat	Cancer
No.	Biopsy (Y/N)	† Year	1st trpl Year	2nd trpl Year	Initial dialysis	Cont on dialysis	CKD5	GFR	GFR Year	Age at intox	Admission Year	BP	Hb	Alb	Inital peak values first w. after intoxication						after intox
1^a	N				N	N	N			47	1979	130/70	116	39	889	0,22	3,6	5	9		N
2^a	N				N	N	N			24	1979	140/80	149	P 71	400	0,19	2,9	9		0,33
3	N		1980		Y	N	Y	35	2011	44	1979	185/100	124		1550	0,3	3	6	37	0,3	Y^b
4	N		1986		Y	N	Y	55	2012	60	1985	170/110	95	P 71	542	0,54	4,1	7,5	23	0,52	Y^c
5	Y				Y	N	N			26	1985	120/80	86		1270	0,3	3	7	17	0,3	N
6^a	N		1987	1999	Y	N	Y	38	2004	21	1985
7	Y		1988	2003	Y	N	Y	107	2009	14	1987	130/80	101		1800				24		N
8	N	2012			N	N	N			40	1987	130/80	144	P 67	126	0,7	2,2	11		0,47
9^a	N				Y	Y	Y			26	1990
10	N				Y	Y	Y			16	1990
11	N		1992	2004	Y	N	Y			39	1991	130/70	123	32	1333	0,47	3	7,4	45	0,23	N
12	N		1992		Y	N	Y			41	1991	130/80	119	32	1074	0,19	3,3	7,9	34	0,17	N
13	N		1992		Y	N	Y			21	1991	135/80	125	45	1458	0,14	2,7	7,5	42	0,24	Y^d
14	N	1999	1983		Y	N	Y			41	1979	160/90	143	41	1630				46
15	N	2000			Y	Y	Y			68	1984	180/95	125	P 72	970	0,3	3	7		0,3
16	N		2000		Y	N	Y	28	2003	28	1999
17	N		2001		Y	N	Y	52	2002	27	1999
18	N		2002		Y	N	Y	44	2012	36	2001				1100	0,3	3	7		0,3	N
19	N	1995			Y	Y	Y	40		60	1984	180/100	111	P 69	970	0,26	2,2	14	10	0,31
20	Y	2007			Y	Y	Y			46	1999
21	N		2013		Y	N	Y			48	2007	129/71			1052	0,28	1,4	6,4	27,6	0,3	N
22	N		2009		Y	N	Y	40	2009	52	2007	174/97									N
23^a	N				N	N	N			25	2010	160/104	115		243	0,45	1,1	6
24	Y		2012		Y	N	Y	11	2012	57	2010	125/87	127	37	2809	0,12	1	7,9			N
25^a	N				Y	Y	Y			61	2011	145/80	98	23	1300				35
26	N				Y	Y	Y			39	2011	150/80	137	30	1081	0,22	0,62	5		0,47	N
27^a	N				N	N	N			48	2011	140/80	152	34	710	0,6	1,3	6,9	25,2	0,72	N
28^a	Y				N	N	N			55	2012	125/80	152	33	473	0,51	1,5	8,2			N

Patient data.^a = no matched control available, F: female, M: male, TRPL: kidney transplantation, CKD: Chronic kidney disease, GFR: measured glomerular filtration rate, BP: blood pressure, Hb: hemoglobin value in g/L, Alb: serum albumin (in some cases protein was measured: P) g/L, Crea: creatinine in umol/L, Alat / Asat / ALP, values measured in μCat/L bilirubin (bil) measured in μmol/L. Liver values reported as normal was estimated (shown in italics). Y^b: Oral cancer, Y^c: Skin cancer, Y^d: Hodgkins Lymphoma

ISSN: 1471-2369