Fig. 2

Sample Collection Flow Diagram and Strategy Design. First morning urine samples were collected 3 times (in 3 consecutive months), labeled as DAY-1, MONTH-2 and MONTH-3, respectively. A randomized spot urine sample was collected in the first day afternoon in the first month, labeled as Random. One more first morning urine sample was collected on the second day in the first month, labeled as DAY-2. Positive test for abnormal ACR was defined as ACR ≥ 30 mg/g creatinine