Table 2 Characteristics of included studies
Author | Country | Setting | Mean age (year) | Boys (%) | Sample size | AKI definition | Location | Storage degreea | Timing of CysC (hours) | Timing of SCr (hours) |
|---|---|---|---|---|---|---|---|---|---|---|
Ali et al. 2013 [42] | USA | Cardiac surgery | 4 | 47.4 | 19 | Urine output of <0.5 | Serum | NR | 12 | 96 |
Al-Tonbary et al. 2004 [43] | Egypt | Cancer | 5.3 | 63.8 | 47 | Decrease in eCCl by at least 20% from baseline | Serum | -20 | 0 | 720 |
Askenazi et al. 2011 [9] | England | Low Birth Weight Infants | 1 | 46.7 | 30 | 50% increase or rise SCr of at least 0.3Â mg/dL | Urine | -20 | 0 | 48 |
Askenazi et al. 2012 [44] | England | ICU admitted | 1 | 51.5 | 33 | 50% increase or rise SCr of at least 0.3Â mg/dL | Urine | -20 | 0 | 48 |
Ataei et al. 2014 [45] | Iran | ICU admitted | 1 | 56.1 | 107 | Decrease in eCCl by at least 25% | Serum | -80 | 0 | 48 |
Benzer et al. 2015 [46] | Turkey | Contrast induced nephropathy | 8.8 | 39.7 | 141 | Decrease in eCCl by at least 25% | Serum | -20 | 0 | 24 |
Di Nardo et al. 2013 [47] | Italy | Sepsis | 2.5 | 36.4 | 11 | Decrease in eCCl by at least 25% | Serum and urine | -80 | 0 to 24 | 48 |
Elmas et al. 2013 [48] | Turkey | Respiratory distress syndrome | 1 | 45.5 | 28 | Cr > 1.5 mg/dL | Serum | -70 | 0 | 72 |
Hamed et al. 2013 [49] | Egypt | ICU admitted | 7 | 53.1 | 32 | GFR < 80 mL/min/1.73 m2 | Serum | -20 | 0 | 24 |
Hassinger et al. 2012 [50] | USA | Cardiac surgery | 7.6 | 55 | 100 | GFR < 80 mL/min/1.73 m2 | Serum | -70 | 0 to 24 | 96 |
Herbert et al. 2015 [51] | USA | Cardiac surgery | 1 | 58.8 | 17 | NGAL > 150 ng/mL | Serum | -20 | 24 | 72 |
Herrero-MorÃn et al. 2007 [52] | Spain | ICU admitted | 2.9 | 60 | 25 | GFR < 80 mL/min/1.73 m2 | Serum | NR | 24 | 24 |
Koyner et al. 2013 [53] | USA | Cardiac surgery | 3.8 | 55 | 299 | 100% rise of Cr | Urine | -80 | 0 to 12 | 24 |
Krawczeski et al. 2010 [54] | USA | Cardiac surgery | 3.5 | 53.5 | 374 | 50% increase or rise SCr of at least 0.3Â mg/dL | Serum | NR | 0 to 24 | 48 |
Lagos-Arevalo et al. 2014 [55] | Canada | ICU admitted | 4.7 | 60 | 160 | 50% increase or rise SCr of at least 0.3Â mg/dL | Urine | -80 | 0 | 48 |
Li et al. 2012 [56] | China | ICU admitted | 0 | 54.8 | 62 | Cr > 1.5 mg/dL | Urine | -80 | Within 240 | 240 |
Mamikonian et al. 2014 [57] | USA | Cardiac surgery | 1.3 | 43 | 40 | Doubling of SCr from baseline | Serum | -80 | 2 to 24 | 24 to 72 |
Maruniak-Chudek et al. 2012 [58] | Poland | ICU admitted | 0 | 62.5 | 32 | 50% increase or rise SCr of at least 0.3Â mg/dL | Serum | -70 | 0 to 24 | 24 to 48 |
McCaffrey et al. 2015 [59] | UK | ICU admitted | 3 | 53 | 49 | Decrease in eCCl by at least 25% | Serum | -80 | 0 | 12 to 24 |
Peco-Antić et al. 2013 [60] | Serbia | Cardiac surgery | 1.6 | 58 | 112 | Decrease in eCCl by at least 25% | Serum | -80 | 0 to 24 | 48 |
Polat et al. 2013 [61] | Turkey | ICU admitted | 8.75 | 44 | 52 | 50% increase or rise SCr of at least 0.3Â mg/dL | Serum | -80 | 0 | 48 |
Sarafidis et al. 2012 [62] | Greece | Asphyxia | 0 | 76.9 | 13 | 50% increase or rise SCr of at least 0.3Â mg/dL | Serum and urine | -80 | 24 | 24 to 72 |
Volpon et al. 2013 [63] | Brazil | ICU admitted | 3.8 | 53.3 | 122 | GFR < 75 mL/min/1.73 m2 | Serum | -80 | 0 to 24 | 72 |
Zhang et al. 2013 [64] | China | Cardiac surgery | 1 | 69.8 | 43 | 50% increase or rise SCr of at least 0.3Â mg/dL | Serum | -80 | 0 to 24 | 72 |