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Table 1 The six domains of the RE-AIM framework and the application to this trial

From: Implementation of a pragmatic randomized trial of screening for chronic kidney disease to improve care among non-diabetic hypertensive veterans

RE-AIM domain

Measure of interest

Ascertainment modality

Reach of target (individual level)

Identification of Patients for Inclusion and Exclusion

Characteristics of enrolled vs. excluded or opt out

Patient characteristics by arm

Proportion who agree to participate

Research coordinator log

Database query

Chart review

Reach of target (setting/organization)

Acknowledgement of research note by PCP

Result Letters Sent

Database Query

Coordinator Log

Effectiveness (individual level)

Proportion Screened

Yield of Testing

Proportion who attend pharmacy visit

BP level

NSAID use

ACE/ARB use

CKD recognition

Questionnaire

Database Query

Pharmacist log

Chart Review

Adoption by target (setting/organization level)

Perceived work flow

Satisfaction with program

Structured Interviews

Email Survey

Implementation (setting/organization level)

Fidelity monitoring

Verify use of treatment algorithm by pharmacist

Structured interviews and questionnaire

Pharmacist log

Maintenance/

Sustainability (provider)

Satisfaction with program

Email questionnaire

Maintenance/

Sustainability (patients)

BP control, use of NSAIDs, ACE/ARB after cessation of intervention

Database query

Resources

Time by pharmacist

Nephrology consultations

Costs

Time logs

VA costs