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Table 3 Clinical characteristics of hemodialyzed patients classified according to the renalase gene polymorphisms

From: Rs10887800 renalase gene polymorphism influences the level of circulating renalase in patients undergoing hemodialysis but not in healthy controls

Variables

POL

Genotypes

p value*

AA

AG

GG

Age (years)

1

64.33 ± 13.26

64.25 ± 14.97

61.69 ± 15.20

>.050

2

65.51 ± 15.07

63.94 ± 13.37

62.95 ± 14.51

>.050

Sex (Male/Female)

1

89/79

62/56

6/17

<.050

2

40/37

78/83

39/32

>.050

BMI (kg/m2)

1

25.50 ± 4.99

25.80 ± 4.64

27.53 ± 9.37

>.050

2

25.62 ± 4.62

25.45 ± 5.13

26.65 ± 6.31

>.050

Albumin (g/dL)

1

3.94 ± .39

3.93 ± .35

3.88 ± .48

>.050

2

3.95 ± .35

3.97 ± .38

3.84 ± .41

>.050

Hemoglobin (g/dL)

1

10.89 ± 1.49

10.90 ± 1.30

10.36 ± 1.22

>.050

2

10.91 ± 1.33

10.96 ± 1.43

10.56 ± 1.42

>.050

Dialysis time (years)

1

6.20 ± 6.46

6.27 ± 5.68

7.65 ± 8.13

>.050

2

5.50 ± 5.49

6.63 ± 6.24

6.59 ± 7.23

>.050

CHOL, n (%)

1

88 (52.38)

57 (48.30)

10 (43.47)

>.050

2

39 (50.64)

83 (51.55)

33 (46.47)

>.050

spKt/Vurea

1

1.38 ± .62

1.39 ± .51

1.36 ± .43

>.050

2

1.37 ± .60

1.37 ± .63

1.39 ± 35

>.050

RD, n (%)

1

67 (39.88)

48 (40.67)

14 (60.86)

>.050

2

28 (36.36)

61 (37.88)

40 (56.33)

<.050

Renalase (μg/mL)

1

33.31 ± 13.01

33.98 ± 11.22

33.09 ± 13.48

>.050

2

29.32a ± 9.89

34.52b ± 13.12

35.91b ± 12.07

<.010

  1. Continuous variables are presented as means ± SD (standard deviation). Discrete variables are presented as numbers and percentages (in parentheses). POL; polymorphism, 1-rs2576178, 2-rs10887800, BMI; Body Mass Index, CHOL; hypercholesterolemia, spKt/Vurea; single-pool Kt/V for urea, RD; residual diuresis. *ANOVA or χ2 tests.