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Table 1 Baseline demographic and laboratory measurements by treatment allocation

From: Effect on non-vascular outcomes of lowering LDL cholesterol in patients with chronic kidney disease: results from the Study of Heart and Renal Protection

 

Simvastatin plus ezetimibe (n = 4650)

Placebo (n = 4620)

Demographics

 Age at randomization (years)a

62 (12)

62 (12)

 Men

2915 (63%)

2885 (62%)

 Ethnicity

  White

3332 (72%)

3314 (72%)

  Black

137 (3%)

127 (3%)

  Chinese

557 (12%)

563 (12%)

  Other Asian

486 (10%)

480 (10%)

  Other/not specified

138 (3%)

136 (3%)

Prior disease

 Prior vascular diseasea

711 (15%)

682 (15%)

 Diabetesa

1054 (23%)

1040 (23%)

 Renal status

  On dialysisa

1534 (33%)

1491 (32%)

   Haemodialysis

1275 (27%)

1253 (27%)

   Peritoneal dialysis

259 (6%)

238 (5%)

  Not on dialysisa

3116 (67%)

3129 (68%)

Baseline measurements

 Total cholesterol (mmol/L)a

4.88 (1.20)

4.90 (1.17)

 LDL cholesterol (mmol/L)a

2.77 (0.88)

2.78 (0.87)

 HDL cholesterol (mmol/L)a

1.12 (0.35)

1.11 (0.34)

 Triglycerides (mmol/L)a

2.31 (1.76)

2.34 (1.68)

 Body mass index (kg/m2)a

27.1 (5.7)

27.1 (5.6)

Renal function

 MDRD-estimated GFR (mL/min/1.73 m2)a,b,c

26.6 (12.9)

26.6 (13.1)

  ≥60

44 (1%)

44 (1%)

  ≥30 to <60

1100 (37%)

1055 (35%)

  ≥15 to <30

1246 (41%)

1319 (44%)

   < 15

613 (20%)

606 (20%)

  Not available

113

105

  1. Data are n (%) or mean (SD)
  2. MDRD Modified Diet in Renal Disease, GFR glomerular filtration rate
  3. aVariables updated at 1 year for patients originally allocated simvastatin only who were rerandomized to simvastatin plus ezetimibe or placebo
  4. bPercentages exclude participants for whom data were not available for that category
  5. cFor patients not on dialysis