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Table 2 Renal function and outcomes between the IHD and CVVHDF groups

From: The impact of continuous renal replacement therapy on renal outcomes in dialysis-requiring acute kidney injury may be related to the baseline kidney function

 

IHD (501)

CVVHDF (992)

P value

APACHE score

19 (16–25)

26 (20–30)

<0.001

Creatinine baseline (mg/dL)a

1.05 (0.8–1.9)

0.9 (0.7–1.2)

<0.001

eGFR baseline (mL/min/1.73 m2)a

69.5 (34.1–100.9)

87.6 (51.1–109.2)

<0.001

Creatinine in the beginning of RRT (mg/dl)

3.7 (3.1–4.5)

3.6 (3.1–4.1)

<0.001

Urea in the beginning of RRT (mg/dL)

139 (106–176)

140 (107–174)

0.596

Death

168 (33.5%)

637 (64.2%)

<0.001

Patients who remained dependent on dialysis at hospital dischargeb

112 (33.6%)

72 (20.3%)

<0.001

eGFR baseline (mL/min/1.73 m2) in dialysis dependence patients

43.3 (26.9–86.0)

85.1 (49.4–99.5)

<0.001

Patients who recovered renal functionb

221 (66.4%)

283 (79.7%)

<0.001

eGFR baseline (mL/min/1.73 m2) in renal recovery patients

79.3 (42.3–107.2)

87.8 (51,7–110.5)

0.101

Creatinine discharge (mg/dL) in renal recovery patients

1.6 (1.1–1.9)

1.3 (1.0–1.8)

0.014

eGFR discharge (mL/min/1,73 m2) in renal recovery patients

46.0 (34.6–68.8)

54.0 (38.7–72.2)

0.011

  1. Values expressed as median (interquartile range) or number (percentage)
  2. IHD intermittent haemodialysis, CVVHDF continuous venovenous hemodiafiltration, APACHE Acute Physiology And Chronic Health Evaluation, eGFR estimated glomerular filtration rate, RRT renal replacement therapy
  3. a488 patients in de IHD group and 960 patients in CVVHDF group
  4. b% values calculated from the number of survivors