Table 3 Comparison of the three periods (time-stratified data)
Evaluated periods | P | ||||||
|---|---|---|---|---|---|---|---|
1999–2003 | 2004–2008 | 2009–2012 | |||||
AKI N (incidence-%) | 271 (2.56%) | 588 (4.77%) | 634 (5.17%) | 0.001 | |||
Liver disease and liver transplant N (%) | |||||||
Cirrhosis/other liver diseases | 21 | 7.70% | 27 | 4.60% | 52 | 8.20% | <0.001 |
Liver transplant | 52 | 19.20% | 197 | 33.50% | 261 | 41.20% | |
Heart disease N (%) | 94 | 34.70% | 228 | 38.80% | 206 | 32.50% | 0.069 |
Malignant solid tumor N (%) | 42 | 15.50% | 78 | 13.30% | 80 | 12.60% | 0.504 |
Solid organ transplant N (%) | 52 | 19.20% | 200 | 34.00% | 274 | 43.20% | <0.001 |
Hematologic malignances and BMT N (%) | 19 | 7.00% | 46 | 7.80% | 42 | 6.60% | 0.715 |
Sepsis-AKI N (%) | 148 | 54.60% | 329 | 56.00% | 362 | 57.10% | 0.779 |
RRT modality N (%) | |||||||
Hemodialysis | 97 | 35.80% | 228 | 38.80% | 176 | 27.80% | <0.001 |
Continuous dialysis | 174 | 64.20% | 360 | 61.20% | 458 | 72.20% | |
Outcomes N (%) | |||||||
Death | 158 | 58.30% | 312 | 53.10% | 335 | 52.80% | 0.352 |
Dialysis dependence | 26 | 9.60% | 81 | 13.80% | 77 | 12.10% | |
Recovery of renal function | 87 | 32.10% | 195 | 33.20% | 222 | 35.00% | |
Vasopressors N (%) | 257 | 94.80% | 558 | 94.90% | 593 | 93.50% | 0.541 |
Mechanical ventilation N (%) | 231 | 85.20% | 502 | 85.40% | 544 | 85.80% | 0.966 |
APACHE II score median (IQR) | 20 | (19–22) | 25 | (18–29) | 26 | (18–31) | <0.001 |
Age (years) mean (SD) | 64 | 18 | 65 | 18 | 61 | 18 | <0.001 |