Table 3 The 15 most commonly prescribed antibiotic regimens
| Â | Antibiotic | Indications | Setting prescribed | Route of administration | Total | No. (%) inappropriate | Reasons for inappropriate classification | ||
|---|---|---|---|---|---|---|---|---|---|
Community | Hospital | IV | Oral | ||||||
1 | Vancomycin | BSI, SSTI, VAI | 2 | 30 | 32 | - | 32 | 3 (9.4) | Incorrect dose/frequency |
2 | Piperacillin/tazobactam | SSTI | - | 23 | 23 | - | 23 | 1 (4.3) | Surgical prophylaxis >24Â h |
3 | Amoxycillin/clavulanic acid | RTI, SSTI | 5 | 15 | - | 20 | 20 | 7 (35.0) | Incorrect dose/frequency, spectrum too broad, incorrect duration |
4 | Cephazolin | BSI, SSTI, VAI | - | 18 | 18 | - | 18 | 10 (55.6) | Incorrect dose/frequency, allergy mismatch, spectrum too narrow, unnecessary antibiotic therapy |
5 | Ceftriaxone | RTI | - | 16 | 16 | - | 16 | 2 (12.5) | Incorrect dose/frequency, spectrum too narrow |
6 | Amoxycillin | RTI, BSI | 11 | 5 | 4 | 12 | 16 | 3 (18.8) | Incorrect dose/frequency, spectrum too narrow, incorrect duration |
7 | Cephalexin | SSTI, UTI | 12 | 2 | - | 14 | 14 | 6 (42.9) | Incorrect dose/frequency, spectrum too broad, microbiology mismatch |
8 | Trimethoprim/sulfamethoxazole | PR | 2 | 11 | - | 13 | 13 | 4 (30.8) | Incorrect dose/frequency |
9 | Doxycycline | RTI | 1 | 12 | - | 13 | 13 | 0 (0.0) | - |
10 | Ciprofloxacin | SSTI, RTI | - | 11 | 1 | 10 | 11 | 4 (36.4) | Incorrect dose/frequency, microbiology mismatch, spectrum too narrow |
11 | Flucloxacillin | VAI, SSTI | 1 | 8 | 5 | 4 | 9 | 2 (22.2) | Incorrect dose/frequency |
12 | Meropenem | RTI, BSI | - | 7 | 7 | - | 7 | 4 (57.1) | Incorrect dose/frequency |
13 | Metronidazole | SSTI | 1 | 5 | 3 | 3 | 6 | 2 (33.3) | Incorrect dose/frequency, unnecessary antibiotic |
14 | Azithromycin | RTI | - | 5 | 5 | - | 5 | 0 (0.0) | - |
15 | Trimethoprim | UTI | 2 | 2 | - | 2 | 4 | 4 (100.0) | Incorrect dose/frequency, incorrect duration |