Classification | Setting | Route of administration | Total | ||
---|---|---|---|---|---|
Community | Hospital | Oral | IV | Â | |
Total assessable | 43/48 (89.6) | 181/187 (96.8) | 102/100 (92.7) | 122/125 (97.6) | 224/235 (95.3) |
Optimal | 13/43 (30.2) | 97/181 (53.6) | 42/102 (41.2) | 68/122 (55.7) | 110/224 (49.1) |
Adequate | 15/43 (34.9) | 44/181 (24.3) | 30/102 (29.4) | 29/122 (23.8) | 59/224 (26.3) |
Inadequate | 15/43 (34.9) | 40/181 (22.1) | 30/102 (29.4) | 25/122 (20.5) | 55/224 (24.6) |
Reasons for inadequate classification | |||||
 Incorrect dose or frequency | 14/15 (93.3) | 29/40 (72.5) | 26/30 (86.7) | 17/25 (68.0) | 43/55 (78.2) |
   Dose too high | 5/14 (35.7) | 7/29 (24.1) | 8/26 (30.8) | 4/17 (23.5) | 12/43 (27.9) |
   Dose too low | 1/14 (7.1) | 1/29 (3.4) | 1/26 (3.8) | 1/17 (5.9) | 2/43 (4.7) |
   Dosing interval too short | 5/14 (35.7) | 17/29 (58.6) | 13/26 (50.0) | 9/17 (52.9) | 22/43 (51.2) |
   Dosing interval too long | 3/14 (21.4) | 4/29 (13.8) | 4/26 (15.4) | 3/17 (17.6) | 7/43 (16.3) |
 Incorrect duration | 3/15 (20.0) | 2/40 (5.0) | 5/30 (16.7) | - | 5/55 (9.1) |
 Allergy mismatch | - | 4/40 (10.0) | - | 4/25 (16.0) | 4/55 (7.3) |
 Spectrum too narrow | 1/15 (6.7) | 3/40 (7.5) | 2/30 (6.7) | 2/25 (8.0) | 4/55 (7.3) |
 Spectrum too broad | 3/15 (20.0) | - | 3/30 (10.0) | - | 3/55 (5.5) |
 Unnecessary antibiotic therapy | - | 3/40 (7.5) | 1/30 (3.3) | 2/25 (8.0) | 3/55 (5.5) |
 Microbiology mismatch | - | 2/40 (5.0) | 2/30 (6.7) | - | 2/55 (3.6) |
 Surgical prophylaxis >24 h | - | 1/40 (2.5) | - | 1/25 (4.0) | 1/55 (1.8) |