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Table 4 The appropriateness of the antibiotic regimens prescribed

From: Patterns of use and appropriateness of antibiotics prescribed to patients receiving haemodialysis: an observational study

Classification

Setting

Route of administration

Total

Community

Hospital

Oral

IV

 

Total assessable

43/48 (89.6)

181/187 (96.8)

102/100 (92.7)

122/125 (97.6)

224/235 (95.3)

Optimal

13/43 (30.2)

97/181 (53.6)

42/102 (41.2)

68/122 (55.7)

110/224 (49.1)

Adequate

15/43 (34.9)

44/181 (24.3)

30/102 (29.4)

29/122 (23.8)

59/224 (26.3)

Inadequate

15/43 (34.9)

40/181 (22.1)

30/102 (29.4)

25/122 (20.5)

55/224 (24.6)

Reasons for inadequate classification

 Incorrect dose or frequency

14/15 (93.3)

29/40 (72.5)

26/30 (86.7)

17/25 (68.0)

43/55 (78.2)

   Dose too high

5/14 (35.7)

7/29 (24.1)

8/26 (30.8)

4/17 (23.5)

12/43 (27.9)

   Dose too low

1/14 (7.1)

1/29 (3.4)

1/26 (3.8)

1/17 (5.9)

2/43 (4.7)

   Dosing interval too short

5/14 (35.7)

17/29 (58.6)

13/26 (50.0)

9/17 (52.9)

22/43 (51.2)

   Dosing interval too long

3/14 (21.4)

4/29 (13.8)

4/26 (15.4)

3/17 (17.6)

7/43 (16.3)

 Incorrect duration

3/15 (20.0)

2/40 (5.0)

5/30 (16.7)

-

5/55 (9.1)

 Allergy mismatch

-

4/40 (10.0)

-

4/25 (16.0)

4/55 (7.3)

 Spectrum too narrow

1/15 (6.7)

3/40 (7.5)

2/30 (6.7)

2/25 (8.0)

4/55 (7.3)

 Spectrum too broad

3/15 (20.0)

-

3/30 (10.0)

-

3/55 (5.5)

 Unnecessary antibiotic therapy

-

3/40 (7.5)

1/30 (3.3)

2/25 (8.0)

3/55 (5.5)

 Microbiology mismatch

-

2/40 (5.0)

2/30 (6.7)

-

2/55 (3.6)

 Surgical prophylaxis >24 h

-

1/40 (2.5)

-

1/25 (4.0)

1/55 (1.8)

  1. All data shown as number of antibiotic regimens and percentage. Reasons for inadequate classification are not mutually exclusive
  2. IV - intravenous