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Table 4 Associations between peritonitis and mortality using the COX proportional hazards regression models

From: The impact of peritoneal dialysis-related peritonitis on mortality in peritoneal dialysis patients

  Univariate model Multivariate model
  HR (95% CI) P value HR (95% CI) P value
All-cause mortality
 Peritonitisa 2.19 (1.68–2.85) <0.001 1.95 (1.46–2.60) <0.001
 Age (per year increase) 1.07 (1.06–1.08) <0.001 1.04 (1.03–1.05) <0.001
 Male gender 0.96 (0.75–1.23) 0.756 1.05 (0.80–1.37) 0.750
 Diabetes mellitus 3.76 (2.95–4.80) <0.001 1.97 (1.48–2.63) <0.001
 History of CVD 4.17 (3.23–5.39) <0.001 2.01 (1.48–2.74) <0.001
 24-h urine output (per 100 ml increase) 0.93 (0.90–0.95) <0.001 0.97 (0.94–0.99) 0.023
 Hemoglobin (g/dL) 0.78 (0.73–0.82) <0.001 0.83 (0.77–0.88) <0.001
 Serum phosphorus (mg/dL) 1.20 (1.13–1.28) <0.001 1.16 (1.08–1.25) <0.001
 Serum albumin (g/dL) 0.39 (0.31–0.49) <0.001 0.83 (0.64–1.07) 0.155
Infection-related mortality
 Peritonitisa 6.00 (3.26–11.03) <0.001 4.94 (2.47–9.86) <0.001
CV mortality
 Peritonitisa 2.05 (1.43–2.93) <0.001 1.90 (1.28–2.81) <0.001
  1. aPeritonitis was parameterized as a time-dependent covariate. Multivariable models for peritonitis were adjusted for age, sex, diabetes, history of CVD, 24-h urine output, hemoglobin, serum phosphorus, and serum albumin.
  2. CVD cardiovascular disease, PD peritoneal dialysis