The impact of peritoneal dialysis-related peritonitis on mortality in peritoneal dialysis patients

BMC Nephrology

Table 4 Associations between peritonitis and mortality using the COX proportional hazards regression models

	Univariate model		Multivariate model
	HR (95% CI)	P value	HR (95% CI)	P value
All-cause mortality
Peritonitis^a	2.19 (1.68–2.85)	<0.001	1.95 (1.46–2.60)	<0.001
Age (per year increase)	1.07 (1.06–1.08)	<0.001	1.04 (1.03–1.05)	<0.001
Male gender	0.96 (0.75–1.23)	0.756	1.05 (0.80–1.37)	0.750
Diabetes mellitus	3.76 (2.95–4.80)	<0.001	1.97 (1.48–2.63)	<0.001
History of CVD	4.17 (3.23–5.39)	<0.001	2.01 (1.48–2.74)	<0.001
24-h urine output (per 100 ml increase)	0.93 (0.90–0.95)	<0.001	0.97 (0.94–0.99)	0.023
Hemoglobin (g/dL)	0.78 (0.73–0.82)	<0.001	0.83 (0.77–0.88)	<0.001
Serum phosphorus (mg/dL)	1.20 (1.13–1.28)	<0.001	1.16 (1.08–1.25)	<0.001
Serum albumin (g/dL)	0.39 (0.31–0.49)	<0.001	0.83 (0.64–1.07)	0.155
Infection-related mortality
Peritonitis^a	6.00 (3.26–11.03)	<0.001	4.94 (2.47–9.86)	<0.001
CV mortality
Peritonitis^a	2.05 (1.43–2.93)	<0.001	1.90 (1.28–2.81)	<0.001

^aPeritonitis was parameterized as a time-dependent covariate. Multivariable models for peritonitis were adjusted for age, sex, diabetes, history of CVD, 24-h urine output, hemoglobin, serum phosphorus, and serum albumin.
CVD cardiovascular disease, PD peritoneal dialysis

ISSN: 1471-2369