Skip to main content

Table 1 Biochemistry parameters before and after haemodialysis (HD)

From: Modern peptide biomarkers and echocardiography in cardiac healthy haemodialysis patients

Parameters

Before HD median (min - max)

After HD median (min - max)

Normal rangea

Significance

Haemoglobin (g/dl)

7.2 (5.5-8.2)

7.4 (5.5-9.1)

7.6-9.5

p = 0.007

Haematokrit (%)

0.36 (0.28-0.41)

0.37 (0.27-0.44)

0.35-0.47

p = 0.229

Potassium (mmol/l)

5.3 (2-6.2)

4.2 (3.6-4.9)

3.3-5.4

p = 0.02

Sodium (mmol/l)

136 (133-147)

137 (132-140)

134-146

p = 0.168

Phosphate (mmol/l)

1.6 (0.8-3.3)

0.9 (0.4-1)

0.9-1.5

p < 0.001

Urea (mmol/l)

23 (10-37)

6 (3-15)

1.7-8.3

p < 0.001

Creatinine (μmol/l)

929 (182-1481)

357 (116-702)

< 80

p < 0.001

Albumin (g/l)

44.5 (37-48)

45 (35-52)

34-48

p = 0.764

Osmolality (mosm/kgH2O)

318 (301-338)

302 (291-326)

280-300

p < 0.001

Aldosterone (ng/l)

148 (35-615)

79 (10-707)

20-150

p = 0.191

Renin active (direct) (ng/l)

12 (1-683)

18 (0.6-1705)

1.68-23.9

p = 0.038

Metanephrine (free) (ng/l)

146 (54-349)

78 (32-308)

< 90

p = 0.001

Normetanephrine (free) (ng/l)

459 (92-822)

188 (75-328)

< 180

p < 0.001

AVP (ng/l)

7.6 (1-9.4)

5.1 (1-9.1)

< 8

p < 0.001

CT-proAVP (pmol/l)

159 (14-291)

63 (8-132)

1-14

p < 0.001

MR-proANP (pmol/l)

814 (285-2908)

665 (222-2144)

46.1-85.2

p < 0.001

NT-proBNP (ng/l)

3020 (522-72,312)

-

< 169

 
  1. Abbreviations: HD haemodialysis, AVP anti-diuretic hormone/vasopressin, CT-proAVP carboxy terminal pro-arginin-vasopressin (copeptin), MR-proANP midregional fragment of the N-terminal of pro-ANP, NT-proBNP N-terminal pro-brain natriuretic peptide, BMI body mass index, K dialyzer clearance of urea, t dialysis time, V volume of distribution of urea approximately equal to patient’s total body water, URR Urea reduction rate, p significance level in Wilcoxon-test
  2. anormal range in healthy patients without HD