Skip to main content

Table 3 Subgroup analysis of unadjusted hazard ratios (HR) associated with eGFR at initial dialysis by age groups

From: Timing of commencement of maintenance dialysis and mortality in young and older adults in Singapore

Age group

eGFR Category

(ml/min/1.73 m2)

Number of overall patients

Number (incidence%) of death

HR (95% CI)

Æ—P value

HR

Æ—P value

Trend

18 to 54 years

Late (<5)

568

107 (18.8)

1.00

 

<0.001

Intermediate (5–10)

309

103 (33.3)

1.96 (1.50–2.57)

<0.001

 

Early (≥10)

42

18 (42.9)

2.78 (1.69–4.58)

<0.001

 

55 to 64 years

Late (<5)

507

153 (30.2)

1.00

 

<0.001

Intermediate (5–10)

427

178 (41.7)

1.52 (1.22–1.88)

<0.001

 

Early (≥10)

61

37 (60.7)

3.27 (2.28–4.69)

<0.001

 

≥65 years

Late (<5)

634

321 (50.6)

1.00

 

<0.001

Intermediate (5–10)

623

354 (56.8)

1.21 (1.04–1.41)

0.014

 

Early (≥10)

115

77 (67.0)

1.67 (1.30–2.14)

<0.001

 
  1. P interaction between age and eGFR at dialysis initiation in unadjusted model was 0.0027.
  2. Æ—P values were derived from Wald test.