Table 1 Baseline Characteristics for All patients and by AKI Status
From: Urinary TIMP-2 and IGFBP7 for the prediction of acute kidney injury following cardiac surgery
All | AKI | No AKI | p value | |
|---|---|---|---|---|
Subjects | 57 | 20 | 37 | |
Male | 41 (71.9%) | 19 (95.0%) | 22 (59.5%) | 0.005 |
Age (Years) | 60 (49–65) | 64 (58–69) | 53 (46–63) | 0.01 |
Comorbidities | ||||
Hypertension | 22 (38.6%) | 13 (65.0%) | 9 (24.3%) | 0.004 |
Diabetes mellitus | 8 (14.0%) | 3 (15.0%) | 5 (13.5%) | >0.99 |
Cerebral infarction | 3 (5.3%) | 2 (10.0%) | 1 (2.7%) | 0.28 |
Hyperlipidemia | 3 (5.3%) | 3 (15.0%) | 0(0%) | 0.04 |
Chronic renal insufficiency | 2 (3.5%) | 2 (10.0%) | 0(0%) | 0.12 |
COPD/Emphysema | 2 (3.5%) | 1 (5.0%) | 1 (2.7%) | >0.99 |
NYHA Class | 0.26 | |||
I | 5 (8.8%) | 1 (5.0%) | 4 (10.8%) | |
II | 24 (42.1%) | 6 (30.0%) | 18 (48.6%) | |
III | 27 (47.4%) | 13 (65.0%) | 14 (37.8%) | |
IV | 1 (1.8%) | 0(0%) | 1 (2.7%) | |
EuroSCORE | 3 (2–4) | 4 (2–5) | 3 (2–3) | 0.09 |
Pre-operative serum creatinine (μmol/L) | 78 (68–87) | 85 (77–88) | 75 (64–84) | 0.02 |
Prior exposure to nephrotoxic drugs | 5 (8.8%) | 3 (15.0%) | 2 (5.4%) | 0.33 |
Prior exposure to radiocontrast agents | 35 (61.4%) | 15 (75.0%) | 20 (54.1%) | 0.16 |
Time from radiocontrast to surgery (d) | 2 (1–5) | 2 (1–3) | 4 (2–6) | 0.03 |
Procedures | ||||
Mitral valve replacement | 17 (29.8%) | 5 (25.0%) | 12 (32.4%) | 0.76 |
Aortic valve replacement | 17 (29.8%) | 12 (60.0%) | 5 (13.5%) | <0.001 |
Coronary artery bypass graft | 12 (21.1%) | 3 (15.0%) | 9 (24.3%) | 0.51 |
Valvuloplasty | 17 (29.8%) | 8 (40.0%) | 9 (24.3%) | 0.24 |
Cardiopulmonary bypass | 42 (73.7%) | 18 (90.0%) | 24 (64.9%) | 0.06 |
CPB time (minutes) | 72 (63–108) | 87 (66–139) | 71 (58–93) | 0.15 |
Aortic cross clamp time (minutes) | 47 (35–66) | 53 (30–92) | 47 (35–63) | 0.50 |
ICU Length of Stay (h) | 23 (20–66) | 34 (21–92) | 22 (20–45) | 0.14 |
Hospital Length of Stay (d) | 12 (10–14) | 12 (9–14) | 12 (10–14) | 0.51 |