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Table 1 Characteristics of the study participants

From: Metabolic syndrome is independently associated with a mildly reduced estimated glomerular filtration rate: a cross-sectional study

  eGFR classifications
Characteristics MRGFR (n = 1479) NGFR (n = 1213) Hyperfiltration (n = 300) P-value
Male, n (%) 640 (43.3) 297 (30.5) 122 (40.7) <0.001
Age (years) 62.71 ± 7.55 59.38 ± 5.72 60.73 ± 5.16 0.064
Current smoking, n (%) 292 (19.7) 153 (12.6) 50 (16.7) <0.001
Drinking, n (%) 256 (17.3) 155 (12.8) 62 (20.7) 0.002
Sodium in taking, n (%) 305 (20.6) 197 (16.3) 56 (18.7) 0.003
Control of Diabetes, n (%) 81 (25.4) 55 (26.5) 19 (25.6) 0.189
Diabetes, n (%) 328 (22.1) 215 (18.8) 74 (20.1) 0.496
Use of ACE inhibitors or ARB, n (%) 87 (5.9) 54 (4.6) 18 (4.9) 0.635
Control of Hypertension, n (%) 415 (70) 252 (75) 68 (77) <0.001
History of Hypertension, n (%) 594 (40.2) 337 (27.8) 90 (30.3) <0.001
Waist circumference (cm) 85.04 ± 9.02 81.51 ± 8.93 84.29 ± 8.03 <0.001
BMI (kg/m2) 24.62 ± 3.03 24.27 ± 3.33 24.86 ± 3.08 0.001
SBP (mmHg) 141.12 ± 33.62 139.09 ± 20.14 140.16 ± 20.84 0.417
DBP (mmHg) 85.12 ± 28.46 83.42 ± 14.56 84.05 ± 14.98 0.179
FPG (mg/dl) 104.76 ± 26.46 102.58 ± 27.36 114.46 ± 37.98 0.001
HbA1c (%) 5.90 ± 0.87 5.90 ± 0.91 6.23 ± 1.23 0.001
TC (mmol/l) 5.21 ± 0.87 5.18 ± 0.85 5.06 ± 0.92 <0.001
TG (mmol/l) 2.14 (0.26,19.82) 1.89 (0.26,10.29) 1.84 (0.48,16.42) <0.001
HDL-c (mmol/l) 1.38 ± 0.56 1.42 ± 0.50 1.42 ± 0.48 <0.001
LDL-c (mmol/l) 2.78 ± 0.73 2.71 ± 0.68 2.56 ± 0.67 <0.001
SUA (mg/dl) 5.22 ± 1.35 4.49 ± 1.16 3.95 ± 1.02 <0.001
BUN (mmol/l) 5.39 ± 1.30 4.99 ± 1.24 4.87 ± 1.27 <0.001
Serum creatinine (mg/dl) 0.89 ± 0.13 0.72 ± 0.09 0.60 ± 0.08 <0.001
eGFR (mL/min/1.73 m2) 78.44 ± 7.67 97.84 ± 3.23 106.27 ± 4.25 <0.001
MS components 0,1,2,3,4,5, (%) 7,24,26,26,14,3 13,25,26,20,13,3 12,26,27,21,12,2 <0.001
  1. Data were presented as means (±SD) or number (%). Means and proportions were compared by ANOVA and Fisher’s exact test, respectively. P values testing the overall difference among eGFR Classifications. NGFR, normal eGFR; MRGFR, mildly reduced GFR; The eGFR Classifications of NGFR, MRGFR and hyperfiltration were in definitions. Definitions of hypertension, diabetes, MS were in methods. Sodium in taking; >6 g/day salt. MS metabolic syndrome, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, HDL high density lipoprotein, LDL low density lipoprotein, FPG fasting plasma glucose, TG Triglycerides, TC Total cholesterol, SUA serum uric acid, BUN, blood urea nitrogen, e-GFR estimated glomerular filtration rate. International system of units (SI) conversion: plasma glucose 1 mg/dl = 1/18 mmol/l; SUA 1 mg/dl = 59.5 mmol/l; Serum creatinine, 1 mg/dL = 88.41umol/L