Metabolic syndrome is independently associated with a mildly reduced estimated glomerular filtration rate: a cross-sectional study

Table 3 Multiple logistic regression analyses of odds ratio for mildly reduced eGFR

Independent variable	Unadjusted		Multivariable adjusted^a
Independent variable	OR (95% CI)	P-value	OR (95% CI)	P-value
1 MS Model
MS Y/N	1.39 (1.20–1.61)	<0.001	1.29 (1.09–1.52)	0.003
2 Number of MS components Model
0	1		1
1	1.64 (1.25–2.16)	<0.001	1.38 (1.02–1.85)	0.035
2	1.85 (1.41–2.43)	<0.001	1.53 (1.14–2.06)	0.004
3	2.30 (1.74–3.03)	<0.001	1.94 (1.44–2.62)	<0.001
4	2.09 (1.54–2.84)	<0.001	1.58 (1.14–2.20)	0.007
5	2.03 (1.25–3.30)	0.004	1.53 (0.91–2.58)	0.111
3 MS components Model
Elevated BP Y/N	1.21 (1.01–1.44)	0.040	1.02 (0.85–1.22)	0.853
Elevated TG Y/N	1.16 (1.00–1.35)	0.049	1.25 (1.05–1.49)	0.011
Decreased HDL Y/N	1.04 (0.84–1.29)	0.742	1.23 (1.03–1.48)	0.025
Obesity Y/N	1.42 (1.22–1.65)	<0.001	1.22 (1.03–1.45)	0.019
Elevated FPG Y/N	0.93 (0.77–1.11)	0.419	0.64 (0.52–0.78)	<0.001
4 MS components + HbA1C Model
B1 (<6.5)	1		1
B2 (≥6.5)	1.21 (1.03–1.42)	0.020	0.56 (0.45–0.70)	<0.001

CI confidence interval, OR odds ratio, MS Metabolic syndrome, BP blood pressure, TG Triglycerides, HDL high density lipoprotein; Obesity, a waist circumference > 90 cm in men and >80 cm in women; FPG fasting plasma glucose, eGFR estimated glomerular filtration rate; ^aAdjusting for age and gender, current smoking, history of hypertension, drinking, use of ACE inhibitors or ARB, control of diabetes and hypertension

ISSN: 1471-2369