Metabolic syndrome is independently associated with a mildly reduced estimated glomerular filtration rate: a cross-sectional study

Table 4 Multiple logistic regression analyses of odds ratio for hyperfiltration

Independent variable	Unadjusted		Multivariable adjusted^a
Independent variable	OR (95% CI)	P-value	OR (95% CI)	P-value
1 MS Model
MS Y/N	0.76 (0.60–0.96)	0.019	0.71 (0.71–1.21)	0.930
2 Number of MS components Model
0	1		1
1	0.80 (0.56–1.15)	0.223	1.06 (0.70–1.60)	0.798
2	0.62 (0.43–0.90)	0.011	0.81 (0.53–1.24)	0.326
3	0.66 (0.45–0.96)	0.029	0.95 (0.61–1.46)	0.798
4	0.44 (0.28–0.70)	0.001	0.73 (0.43–1.25)	0.249
5	0.51 (0.23–1.12)	0.094	0.89 (0.36–2.19)	0.797
3 MS components Model
Elevated BP Y/N	0.82 (0.65–1.04)	0.100	0.98 (0.74–1.30)	0.844
Elevated TG Y/N	0.62 (0.49–0.79)	<0.001	0.56 (1.42–1.75)	<0.001
Decreased HDL Y/N	1.33 (1.04–1.70)	0.025	1.07 (1.81–1.42)	0.638
Obesity Y/N	0.69 (0.54–0.88)	0.002	0.98 (0.69–1.21)	0.527
Elevated FPG Y/N	1.05 (0.79–1.40)	0.717	1.53 (1.30–1.81)	<0.001
4 MS components + HbA1C Model
B1 (<6.5)	1		1
B2 (≥6.5)	1.50 (1.11–2.02)	0.008	2.86 (2.0–4.09)	0.000

CI confidence interval, OR odds ratio, MS Metabolic syndrome, BP blood pressure, TG Triglycerides, HDL high density lipoprotein, Obesity a waist circumference > 90 cm in men and >80 cm in women, FPG fasting plasma glucose; ^aAdjusting for age and gender, current smoking, history of hypertension, drinking, use of ACE inhibitors or ARB, control of diabetes and hypertension

ISSN: 1471-2369