Serum micro-rna profiles in patients with autosomal dominant polycystic kidney disease according to hypertension and renal function

Table 1 Comparison of demographical and biochemical data between ADPKD patients (n = 80) and healthy controls (n = 50)

Clinical Parameters	ADPKD patients (n = 80)	Healthy controls (n = 50)	p
Age, year	44.6 ± 12.7	45.4 ± 12.7	0.35
Gender, F/M	33/47	22/28	0.12
Hemoglobin, g/L	13.9 ± 2.1	13.3 ± 1.9	0.74
BMI (kg/m²)	27.6 ± 5.37	26.74 ± 7.8	0.21
Average 24-h systolic BP, mmHg	139 ± 7.2	119 ± 6.1	0.005
Average 24-h diastolic BP, mmHg	86 ± 4.8	73 ± 3.9	0.01
eGFR^a, mL/min per 1.73 m²	74.0 ± 35.4	98.1 ± 15.3	<0.001
Smoking, n(%)	18 (22)	10 (20)	0.54
Fasting Total cholesterol, mg/dL	197 ± 39	184 ± 33	0.19
HDL- cholesterol, mg/dL	42 ± 10	46 ± 8	0.23
LDL- cholesterol, mg/dL	124 ± 30	119 ± 36	0.63
Proteinuria, g/day	0.47 (0.12–1.19)	0.15 (0.07–0.6)	<0.001
Hs-CRP, mg/L	6.9 ± 2.7	3.5 ± 1.6	0.01
Albumin (g/dL)	3.9 ± 0.61	4.1 ± 0.62	0.72

ADPKD Autosomal-dominant polycystic kidney disease, eGFR estimated glomerular filtration rate, F/M Female/Male, HDL High density lipoprotein, Hs-CRP High sensitive C-reactive protein, LDL Low density lipoprotein
^aCalculated by the CKD-EPI formula
Data are expressed as mean ± SD or median for normally distributed data and percentage (%) for categorical variables.
Bold values indicate the significant values (p < 0.05)

ISSN: 1471-2369