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Table 2 Comparison of demographical and laboratory features between the 28 ADPKD patients without (HT-) and the 52 patients with (HT+) hypertension (defined as average systolic pressure was ≥130 mmHg and/or the average diastolic pressure was ≥80 mmHg during 24-h, or if the individual was taking antihypertensive medication [n = 10])

From: Serum micro-rna profiles in patients with autosomal dominant polycystic kidney disease according to hypertension and renal function

Variables

ADPKD patients (n = 80)

p

Non-hypertensives (n = 28)

Hypertensives (n = 52)

Age (years)

32.7 ± 8.8

47.9 ± 11.4

<0.001

Gender (male)

15 (53.0)

32 (61)

0.07

Hemoglobin, g/l

13.4 ± 1.5

14.0 ± 1.7

0.22

BMI (kg/m2)

26.6 ± 5.37

29.74 ± 7.8

0.109

Average 24-h systolic BP, mmHg

124 ± 4.6

150 ± 9.1

<0.001

Average 24-h diastolic BP, mmHg

73 ± 3.9

98 ± 7.4

<0.001

Smoking status, n(%)

6 (21)

12 (23)

0.701

eGFRa ml/min/1.73 m2

108 (85–116)

58.5 (21–91)

<0.001

Fasting total cholesterol, mg/dl

178.7 ± 41.7

201.79 ± 33.00

0.02

Fasting LDL-C, mg/dl

113.3 ± 40.4

124.3 ± 30.6

0.17

Proteinuria, g/day

0.20(0.12–0.33)

0.70(0.4–1.19)

<0.001

Albumin (g/dL)

4.0 ± 0.61

3.9 ± 0.54

0.66

  1. ADPKD Autosomal-dominant polycystic kidney disease, BMI Body mass index, eGFR estimated glomerular filtration rate, LDL Low density lipoprotein
  2. Values are expressed as n(%), mean ± SD or median(1st-3rd quartiles).
  3. aCalculated by the CKD-EPI formula
  4. Bold values indicate the significant values (p<0.05)