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Table 2 Bivariate regression analysis between patients with baseline dp-ucMGP <5000 and those >5000 pM

From: High Dephosphorylated-Uncarboxylated MGP in Hemodialysis patients: risk factors and response to vitamin K2, A pre-post intervention clinical trial

 

Baseline dp-ucMGP <5000 N = 41

Baseline dp-ucMGP >5000 N = 9

P-value

Age (years), median (IQR)

69.0 (56.5; 76.5)

80.0 (57.0; 82.5)

0.18

Gender, male n (%)

28 (68.3)

2 (22.2)

0.02

Dialysis vintage (months), median (IQR)

43.0 (20.5; 104.0)

82.0 (41.0; 134.0)

0.18

Diabetes, n (%)

16 (39.0)

2 (22.2)

0.46

Hypertension, n (%)

34 (82.9)

4 (44.4)

0.03

Smoking, n (%)

6 (14.6)

2 (22.2)

0.62

Calcification score, median (IQR)

7.0 (2.0; 12.5)

13.0 (2.5; 21.0)

0.25

NCBB, n (%)

16 (39.0)

4 (44.4)

1.00

Residual diuresis, n (%)

5 (12.2)

1 (11.1)

1.00

Calcium dose (tablets of 600 mg), median (IQR)

1.0 (1.0; 3.0)

1.0 (0.0; 1.0)

0.055

Alfacalcidol dose (μg), median (IQR)

0.75 (0.00; 1.25)

1.0 (0.5; 5.0)

0.08

Serum phosphate (mg/dl), median (IQR)

3.9 (3.3; 4.8)

3.90 (2.75; 4.40)

0.29

Serum calcium (mg/dl), median (IQR)

9.1 (8.8; 9.3)

9.2 (8.8; 9.6)

0.40

PTH (pg/ml), median (IQR)

163.0 (95.2; 260.0)

197.0 (165.5; 397.0)

0.27

LDL cholesterol (mg/dl), median (IQR)

92.0 (77.0; 113.0)

92.0 (67.0; 113.0)

0.82

BMI, median (IQR)

25.6 (22.8; 27.8)

26.16 (23.35; 33.56)

0.18

URR, median (IQR)

74.0 (71.0; 78.0)

77.0 (75.0; 80.5)

0.08

Albumin, median (IQR)

39.0 (37.0; 41.5)

36.5 (34.0; 39.0)

0.046

CAD, n (%)

11 (26.8)

3 (33.3)

0.70

Cinacalcet, n (%)

1 (2.4)

1 (11.1)

0.33

Previous acenocoumadin, n (%)

4 (9.8)

2 (22.2)

0.29

PTHX, n (%)

2 (4.9)

0 (0.0)

1.00

Recent fracture, n (%)

0 (0.0)

3 (33.3)

0.004

  1. Abbreviations: NCBB non-calcium-based phosphate binders, PTH intact parathyroid hormone, BMI body mass index, URR urea reduction ratio, CAD documented coronary artery disease, PTHX previous parathyroidectomy