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Table 2 Bivariate regression analysis between patients with baseline dp-ucMGP <5000 and those >5000 pM

From: High Dephosphorylated-Uncarboxylated MGP in Hemodialysis patients: risk factors and response to vitamin K2, A pre-post intervention clinical trial

  Baseline dp-ucMGP <5000 N = 41 Baseline dp-ucMGP >5000 N = 9 P-value
Age (years), median (IQR) 69.0 (56.5; 76.5) 80.0 (57.0; 82.5) 0.18
Gender, male n (%) 28 (68.3) 2 (22.2) 0.02
Dialysis vintage (months), median (IQR) 43.0 (20.5; 104.0) 82.0 (41.0; 134.0) 0.18
Diabetes, n (%) 16 (39.0) 2 (22.2) 0.46
Hypertension, n (%) 34 (82.9) 4 (44.4) 0.03
Smoking, n (%) 6 (14.6) 2 (22.2) 0.62
Calcification score, median (IQR) 7.0 (2.0; 12.5) 13.0 (2.5; 21.0) 0.25
NCBB, n (%) 16 (39.0) 4 (44.4) 1.00
Residual diuresis, n (%) 5 (12.2) 1 (11.1) 1.00
Calcium dose (tablets of 600 mg), median (IQR) 1.0 (1.0; 3.0) 1.0 (0.0; 1.0) 0.055
Alfacalcidol dose (μg), median (IQR) 0.75 (0.00; 1.25) 1.0 (0.5; 5.0) 0.08
Serum phosphate (mg/dl), median (IQR) 3.9 (3.3; 4.8) 3.90 (2.75; 4.40) 0.29
Serum calcium (mg/dl), median (IQR) 9.1 (8.8; 9.3) 9.2 (8.8; 9.6) 0.40
PTH (pg/ml), median (IQR) 163.0 (95.2; 260.0) 197.0 (165.5; 397.0) 0.27
LDL cholesterol (mg/dl), median (IQR) 92.0 (77.0; 113.0) 92.0 (67.0; 113.0) 0.82
BMI, median (IQR) 25.6 (22.8; 27.8) 26.16 (23.35; 33.56) 0.18
URR, median (IQR) 74.0 (71.0; 78.0) 77.0 (75.0; 80.5) 0.08
Albumin, median (IQR) 39.0 (37.0; 41.5) 36.5 (34.0; 39.0) 0.046
CAD, n (%) 11 (26.8) 3 (33.3) 0.70
Cinacalcet, n (%) 1 (2.4) 1 (11.1) 0.33
Previous acenocoumadin, n (%) 4 (9.8) 2 (22.2) 0.29
PTHX, n (%) 2 (4.9) 0 (0.0) 1.00
Recent fracture, n (%) 0 (0.0) 3 (33.3) 0.004
  1. Abbreviations: NCBB non-calcium-based phosphate binders, PTH intact parathyroid hormone, BMI body mass index, URR urea reduction ratio, CAD documented coronary artery disease, PTHX previous parathyroidectomy