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Table 4 Bivariate regression analysis between patients with baseline dp-ucMGP <3000 and those >3000 pM

From: High Dephosphorylated-Uncarboxylated MGP in Hemodialysis patients: risk factors and response to vitamin K2, A pre-post intervention clinical trial

  Baseline dp-ucMGP <3000 N = 24 Baseline dp-ucMGP >3000 N = 26 P-value
Age (years), median (IQR) 69.0 (53.5; 76.5) 73.5 (61.7; 80.0) 0.28
Gender, male n (%) 17 (70.8) 13 (50.0) 0.16
Dialysis vintage (months), median (IQR) 40.0 (17.0; 99.2) 49.5 (37.7; 119.0) 0.15
Diabetes, n (%) 11 (45.8) 7 (26.9) 0.24
Hypertension, n (%) 18 (75.0) 20 (76.9) 1.00
Smoking, n (%) 3 (12.5) 5 (19.2) 0.70
Calcification score, median (IQR) 4.5 (1.0; 10.7) 10.5 (3.7; 15.2) 0.04
NCBB, n (%) 11 (45.8) 9 (34.6) 0.56
Residual diuresis, n (%) 4 (16.7) 2 (7.7) 0.41
Calcium dose (tablets of 600 mg), median (IQR) 2.0 (1.0; 3.0) 1.0 (1.0; 2.0) 0.10
Alfacalcidol dose (μg), median (IQR) 0.75 (0.00; 1.50) 0.75 (0.25; 1.50) 0.69
Serum phosphate (mg/dl), median (IQR) 3.85 (3.50; 5.07) 3.9 (3.0; 4.5) 0.20
Serum calcium (mg/dl), median (IQR) 9.0 (8.7; 9.3) 9.15 (8.90; 9.32) 0.13
PTH (pg/ml), median (IQR) 158.5 (97.1; 260.2) 205.0 (126.0; 319.0) 0.38
LDL cholesterol (mg/dl), median (IQR) 93.5 (77.7; 115.0) 92.0 (76.0; 113.0) 0.56
BMI (Kg/m2), median (IQR) 25.57 (22.74; 29.64) 26.02 (22.76; 28.42) 0.74
URR, median (IQR) 75.0 (69.5; 78.7) 75.00 (71.25; 79.25) 0.76
Albumin, median (IQR) 39.0 (35.2; 41.0) 38.50 (36.00; 41.25) 0.99
CAD, n (%) 6 (25.0) 8 (30.8) 0.76
Cinacalcet, n (%) 1 (4.2) 1 (3.8) 1.00
Previous acenocoumadin, n (%) 3 (12.5) 3 (11.5) 1.00
PTHX, n (%) 0 (0.0) 2 (7.7) 0.49
Recent fracture, n (%) 0 (0.0) 3 (11.5) 0.24
  1. Abbreviations: NCBB non-calcium-based phosphate binders, PTH intact parathyroid hormone, BMI body mass index, URR urea reduction ratio, CAD documented coronary artery disease, PTHX previous parathyroidectomy