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Table 4 Bivariate regression analysis between patients with baseline dp-ucMGP <3000 and those >3000 pM

From: High Dephosphorylated-Uncarboxylated MGP in Hemodialysis patients: risk factors and response to vitamin K2, A pre-post intervention clinical trial

 

Baseline dp-ucMGP <3000 N = 24

Baseline dp-ucMGP >3000 N = 26

P-value

Age (years), median (IQR)

69.0 (53.5; 76.5)

73.5 (61.7; 80.0)

0.28

Gender, male n (%)

17 (70.8)

13 (50.0)

0.16

Dialysis vintage (months), median (IQR)

40.0 (17.0; 99.2)

49.5 (37.7; 119.0)

0.15

Diabetes, n (%)

11 (45.8)

7 (26.9)

0.24

Hypertension, n (%)

18 (75.0)

20 (76.9)

1.00

Smoking, n (%)

3 (12.5)

5 (19.2)

0.70

Calcification score, median (IQR)

4.5 (1.0; 10.7)

10.5 (3.7; 15.2)

0.04

NCBB, n (%)

11 (45.8)

9 (34.6)

0.56

Residual diuresis, n (%)

4 (16.7)

2 (7.7)

0.41

Calcium dose (tablets of 600 mg), median (IQR)

2.0 (1.0; 3.0)

1.0 (1.0; 2.0)

0.10

Alfacalcidol dose (μg), median (IQR)

0.75 (0.00; 1.50)

0.75 (0.25; 1.50)

0.69

Serum phosphate (mg/dl), median (IQR)

3.85 (3.50; 5.07)

3.9 (3.0; 4.5)

0.20

Serum calcium (mg/dl), median (IQR)

9.0 (8.7; 9.3)

9.15 (8.90; 9.32)

0.13

PTH (pg/ml), median (IQR)

158.5 (97.1; 260.2)

205.0 (126.0; 319.0)

0.38

LDL cholesterol (mg/dl), median (IQR)

93.5 (77.7; 115.0)

92.0 (76.0; 113.0)

0.56

BMI (Kg/m2), median (IQR)

25.57 (22.74; 29.64)

26.02 (22.76; 28.42)

0.74

URR, median (IQR)

75.0 (69.5; 78.7)

75.00 (71.25; 79.25)

0.76

Albumin, median (IQR)

39.0 (35.2; 41.0)

38.50 (36.00; 41.25)

0.99

CAD, n (%)

6 (25.0)

8 (30.8)

0.76

Cinacalcet, n (%)

1 (4.2)

1 (3.8)

1.00

Previous acenocoumadin, n (%)

3 (12.5)

3 (11.5)

1.00

PTHX, n (%)

0 (0.0)

2 (7.7)

0.49

Recent fracture, n (%)

0 (0.0)

3 (11.5)

0.24

  1. Abbreviations: NCBB non-calcium-based phosphate binders, PTH intact parathyroid hormone, BMI body mass index, URR urea reduction ratio, CAD documented coronary artery disease, PTHX previous parathyroidectomy