Skip to main content

Table 5 Bivariate regression analysis: variables associated with the dp-ucMGP drop divided by the median (90%)

From: High Dephosphorylated-Uncarboxylated MGP in Hemodialysis patients: risk factors and response to vitamin K2, A pre-post intervention clinical trial

 

Dp-ucMGP drop ≤90% N = 23

Dp-ucMGP drop >90% N = 27

P-value

OR (95% CI)

Age (years), Median (IQR)

72.0 (55.0; 80.0)

69.0 (63.0; 79.0)

0.63

1.01 (0.97–1.05)

Gender, male n (%)

14 (60)

16 (59.3)

1.00

1.07 (0.34–3.33)

Dialysis vintage (months), Median (IQR)

41.0 (28.0; 112.0)

48.0 (22.0; 110.0)

0.68

1.02 (0.92–1.14)

Diabetes, n (%)

13 (56.5)

5 (18.5)

0.01

0.17 (0.05–0.62)

Hypertension, n (%)

16 (69.6)

22 (81.5)

0.32

1.92 (0.52–7.18)

Smoking, n (%)

3 (13.0)

5 (18.5)

0.71

1.51 (0.32–7.17)

Calcification score, Median (IQR)

3.0 (1.0; 12.0)

9.0 (4.0; 14.0)

0.10

1.06 (0.97–1.15)

NCBB, n (%)

10 (43.5)

10 (37.0)

0.64

0.76 (0.25–2.38)

Residual diuresis, n (%)

3 (13.0)

3 (11.1)

1.00

0.83 (0.15–4.59)

Calcium dose, Median (IQR)

2.0 (1.0; 3.0)

1.0 (1.0; 2.0)

0.12

0.63 (0.36–1.11)

Alfacalcidol dose (μg), Median (IQR)

0.75 (0.00; 1.50)

0.75 (0.25; 1.50)

0.20

1.17 (0.82–1.69)

Serum phosphate (mg/dl), Median (IQR)

3.90 (3.50; 5.00)

3.90 (3.00; 4.50)

0.25

0.64 (0.39–1.06)

Serum calcium (mg/dl), Median (IQR)

9.00 (8.70; 9.30)

9.20 (8.90; 9.30)

0.08

4.97 (0.82–30.06)

PTH (pg/ml), Median (IQR)

153.00 (88.50; 216.00)

216.0 (144.0; 314.0)

0.10

1.03 (0.98–1.07)

LDL cholesterol (mg/dl), Median (IQR)

93.50 (77.75; 114.25)

92.00 (76.00; 113.25)

0.61

0.99 (0.97–1.02

BMI (Kg/m2), Median (IQR)

26.45 (23.03; 31.39)

25.26 (22.65; 26.65)

0.13

0.89 (0.78–1.01)

URR, Median (IQR)

75.0 (71.0; 79.0)

74.0 (71.0; 79.0)

0.70

0.98 (0.88–1.10)

Albumin, Median (IQR)

37.0 (35.0; 40.0)

39.0 (37.0; 41.0)

0.15

1.09 (0.94–1.26)

CAD, n (%)

7 (30.4)

7 (25.9)

0.72

0.80 (0.23–2.76)

Cinacalcet, n (%)

1 (4.3)

1 (3.7)

1.00

0.85 (0.05–14.33)

Previous acenocoumadin, n (%)

3 (13.0)

3 (11.1)

1.00

0.83 (0.15–4.59)

PTHX, n (%)

0 (0.0)

2 (7.4)

0.49

NA

Recent fracture, n (%)

1 (4.3)

2 (7.4)

1.00

1.76 (0.15–20.76)

  1. Abbreviations: NCBB non-calcium-based phosphate binders, PTH intact parathyroid hormone, BMI body mass index, URR urea reduction ratio, CAD documented coronary artery disease, PTHX, previous parathyroidectomy