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Table 3 Multivariate analysis

From: C-terminal fragment of agrin (CAF) levels predict acute kidney injury after acute myocardial infarction

 

Multivariate analysis

OR

95%CI

P value

Age

1.03

0.99-1.07

0.165

Diabetes Mellitus

1.83

0.96-3.51

0.067

CPK peak levels (IU/L)

1.01

0.99-1.02

0.056

Hemoglobin (g/dL)

0.81

0.65-0.99

0.003

GFR baseline (ml/min)

1.01

0.99-1.02

0.194

Albuminuria

  

0.295

 0-30 mg/g

  

n/a

 30-300 mg/g

1.43

0.73-2.81

0.302

  > 300 mg/g

2.09

0.79-5.46

0.133

LV Ejection fraction

  

0.002

  Normal (>55%)

  

n/a

  Mildly reduced (45-55%)

2.01

0.98-4.12

0.057

  Moderately reduced (35-44%)

3.64

1.71-9.77

0.001

  Severely reduced (<35%)

7.58

1.45-39.29

0.016

Invasive vs conservative treatment

0.88

0.46-1.68

0.691

Presence of adverse event

1.56

0.78-3.12

0.208

  1. Presence of adverse events refer to recurrent ischemia, re-infarction, hemodynamic collapse, tachyarrhythmia requiring intervention, bradyarrhythmia requiring intervention, acute heart failure during hospitalization, major bleeding complications, acute mitral valve regurgitation (severe), pericarditis
  2. The method use was backward deletion method using the Likelihood Ratio criterion according which all variables were entered in the model and for each step the worse performing variable (according to the criterion used) was discarded. Therefore, the significant variables were, except from CAF22, hemoglobin levels, LV ejection fraction, and marginally diabetes mellitus and myocardial infract size (using CPK peak levels)