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Table 3 Multivariate analysis

From: C-terminal fragment of agrin (CAF) levels predict acute kidney injury after acute myocardial infarction

  Multivariate analysis
OR 95%CI P value
Age 1.03 0.99-1.07 0.165
Diabetes Mellitus 1.83 0.96-3.51 0.067
CPK peak levels (IU/L) 1.01 0.99-1.02 0.056
Hemoglobin (g/dL) 0.81 0.65-0.99 0.003
GFR baseline (ml/min) 1.01 0.99-1.02 0.194
Albuminuria    0.295
 0-30 mg/g    n/a
 30-300 mg/g 1.43 0.73-2.81 0.302
  > 300 mg/g 2.09 0.79-5.46 0.133
LV Ejection fraction    0.002
  Normal (>55%)    n/a
  Mildly reduced (45-55%) 2.01 0.98-4.12 0.057
  Moderately reduced (35-44%) 3.64 1.71-9.77 0.001
  Severely reduced (<35%) 7.58 1.45-39.29 0.016
Invasive vs conservative treatment 0.88 0.46-1.68 0.691
Presence of adverse event 1.56 0.78-3.12 0.208
  1. Presence of adverse events refer to recurrent ischemia, re-infarction, hemodynamic collapse, tachyarrhythmia requiring intervention, bradyarrhythmia requiring intervention, acute heart failure during hospitalization, major bleeding complications, acute mitral valve regurgitation (severe), pericarditis
  2. The method use was backward deletion method using the Likelihood Ratio criterion according which all variables were entered in the model and for each step the worse performing variable (according to the criterion used) was discarded. Therefore, the significant variables were, except from CAF22, hemoglobin levels, LV ejection fraction, and marginally diabetes mellitus and myocardial infract size (using CPK peak levels)