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Table 2 Associations of baseline hs-CRP and adjusted variablesa with all-cause and CVD mortality

From: Association of baseline, longitudinal serum high-sensitive C-reactive protein and its change with mortality in peritoneal dialysis patients

 

All-cause mortality

CVD mortality

HR (95% CI)

P value

HR (95% CI)

P value

hs-CRP

 Log hs-CRP(per 1 mmol/L)

1.19 (0.89–1.60)

0.246

1.50 (1.00–2.24)

0.048

 hs-CRP tertile 1

Ref.

-

Ref.

-

 hs-CRP tertile 2

1.09 (0.71–1.66)

0.692

1.39 (0.77–2.53)

0.273

 hs-CRP tertile 3

1.26 (0.83–1.90)

0.273

1.63 (0.90–2.93)

0.104

Age (per 1 year)

1.04 (1.03–1.06)

<0.001

1.04 (1.02–1.06)

<0.001

Sex (female versus male)

0.85 (0.63–1.16)

0.304

0.79 (0.53–1.18)

0.248

BMI (per 1 kg/m2)

1.02 (0.96–1.08)

0.485

1.08(1.01–1.16)

0.025

MBP (per 10 mmHg)

1.03 (0.94–1.14)

0.497

1.03 (0.91–1.17)

0.591

CVD (yes versus no)

2.43 (1.77–3.34)

<0.001

3.35 (2.15–5.21)

<0.001

DM (yes versus no)

2.03 (1.45–2.85)

<0.001

1.94 (1.26–3.01)

0.003

HGB (per 10 g/L)

0.92 (0.85–1.01)

0.070

0.94 (0.84–1.05)

0.237

ALB (per 1 g/L)

0.94 (0.91–0.98)

0.003

0.94 (0.90–0.99)

0.023

UA (per 10 μmol/L)

1.01 (0.99–1.03)

0.257

1.00 (0.98–1.03)

0.844

TG (per 1 mmol/L)

1.12 (1.02–1.24)

0.021

1.13 (1.00–1.28)

0.054

rGFR (per 1 ml/min/1.73 m2)

0.94 (0.89–1.00)

0.058

0.92 (0.85–1.00)

0.043

  1. a Variable that demonstrated an unadjusted P value of <0.10 in univariate Cox proportional hazard regression analyses or for importance of clinical concern was included in the this model.
  2. Abbreviations: BMI body mass index; MAP mean arterial pressure; CVD cardiovascular disease; DM diabetes mellitus; HGB hemoglobin;
  3. ALB serum albumin; UA uric acid; TG triglyceride; rGFR residual glomerular filtration rate.