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Table 1 Patient characteristics

From: Circulating osteoprotegerin is associated with chronic kidney disease in hypertensive patients

Parameter CNT (n = 141) CKD (n = 42) p-value
Age (years) 59.5 ± 7.7 60.1 ± 8.5 0.6467
Sex (% male) 68.1 5.7 0.0253
BMI (Kg/m2) 28.0 ± 4.6 25.4 ± 3.4 0.0002
SBP (mmHg) 155.2 ± 18.3 167.7 ± 21.6 0.0003
DBP (mmHg) 92.3 ± 9.2 94.9 ± 15.3 0.2987
Hypertension duration (months) 193 ± 94 212 ± 104 0.4558
Creatinine (mg/dL) 1.0 ± 0.1 3.4 ± 1.6 0.0001
GFR (mL/min) 69.0 ± 12.9 24.0 ± 13.1 <.0001
Urea nitrogen (mg/dL) 36.6 ± 9.3 94.9 ± 64.0 <.0001
Uric acid (mg/dL) 5.4 ± 1.4 7.1 ± 1.8 <.0001
Proteinuria (g/24 h) - 1.3 ± 1.1  
AER (μg/min) 22.3 ± 45.0 -  
Glucose (mg/dL) 98.9 ± 1.7 93.4 ± 2.9 0.1188
Sodium (mEq/L) 140.6 ± 2.4 141.1 ± 2.8 0.2772
Potassium (mEq/L) 4.2 ± 0.3 4.6 ± 0.5 <.0001
Calcium (mg/dL) 5.2 ± 0.5 5.2 ± 0.8 0.9838
Phosphate (mg/dL) 2.8 ± 0.6 3.6 ± 1.5 0.0019
PTH (pg/mL) 33.7 ± 16.8 114.2 ± 110.6 <.0001
Total cholesterol (mg/dL) 235.3 ± 44.0 219.9 ± 50.8 0.0563
HDL cholesterol (mg/dL) 51.9 ± 15.0 44.2 ± 13.2 0.0032
Triglycerides (mg/dL) 148.1 ± 90.6 177.6 ± 69.1 0.2840
LDL cholesterol (mg/dL) 153.7 ± 40.2 140.1 ± 46.0 0.0892
CRP (mg/L) 3.9 ± 7.8 9.3 ± 11.31 0.0044
ACEi or/ARB (%) 52.5 35.7 0.0563
Macrovascular events (%) 12.8 54.8 <.0001
  1. ACEi is for ACE inhibitors, AER is for albumin excretion rate, ARB is for AngiotensinII receptor blockers, BMI is for body mass index, CKD is for chronic kidney disease, CNT is for control, CRP is for C-reactive protein, DBP is for diastolic blood pressure, GFR is for glomerular filtration rate, HDL is for high density lipoprotein, LDL is for low density lipoprotein, PTH is for parathormone, SBP is for systolic blood pressure. Macrovascular events include acute myocardial infarction, peripheral artery disease, and stroke.