Table 1 Patient characteristics
From: Circulating osteoprotegerin is associated with chronic kidney disease in hypertensive patients
Parameter | CNT (n = 141) | CKD (n = 42) | p-value |
|---|---|---|---|
Age (years) | 59.5 ± 7.7 | 60.1 ± 8.5 | 0.6467 |
Sex (% male) | 68.1 | 5.7 | 0.0253 |
BMI (Kg/m2) | 28.0 ± 4.6 | 25.4 ± 3.4 | 0.0002 |
SBP (mmHg) | 155.2 ± 18.3 | 167.7 ± 21.6 | 0.0003 |
DBP (mmHg) | 92.3 ± 9.2 | 94.9 ± 15.3 | 0.2987 |
Hypertension duration (months) | 193 ± 94 | 212 ± 104 | 0.4558 |
Creatinine (mg/dL) | 1.0 ± 0.1 | 3.4 ± 1.6 | 0.0001 |
GFR (mL/min) | 69.0 ± 12.9 | 24.0 ± 13.1 | <.0001 |
Urea nitrogen (mg/dL) | 36.6 ± 9.3 | 94.9 ± 64.0 | <.0001 |
Uric acid (mg/dL) | 5.4 ± 1.4 | 7.1 ± 1.8 | <.0001 |
Proteinuria (g/24 h) | - | 1.3 ± 1.1 |  |
AER (μg/min) | 22.3 ± 45.0 | - |  |
Glucose (mg/dL) | 98.9 ± 1.7 | 93.4 ± 2.9 | 0.1188 |
Sodium (mEq/L) | 140.6 ± 2.4 | 141.1 ± 2.8 | 0.2772 |
Potassium (mEq/L) | 4.2 ± 0.3 | 4.6 ± 0.5 | <.0001 |
Calcium (mg/dL) | 5.2 ± 0.5 | 5.2 ± 0.8 | 0.9838 |
Phosphate (mg/dL) | 2.8 ± 0.6 | 3.6 ± 1.5 | 0.0019 |
PTH (pg/mL) | 33.7 ± 16.8 | 114.2 ± 110.6 | <.0001 |
Total cholesterol (mg/dL) | 235.3 ± 44.0 | 219.9 ± 50.8 | 0.0563 |
HDL cholesterol (mg/dL) | 51.9 ± 15.0 | 44.2 ± 13.2 | 0.0032 |
Triglycerides (mg/dL) | 148.1 ± 90.6 | 177.6 ± 69.1 | 0.2840 |
LDL cholesterol (mg/dL) | 153.7 ± 40.2 | 140.1 ± 46.0 | 0.0892 |
CRP (mg/L) | 3.9 ± 7.8 | 9.3 ± 11.31 | 0.0044 |
ACEi or/ARB (%) | 52.5 | 35.7 | 0.0563 |
Macrovascular events (%) | 12.8 | 54.8 | <.0001 |