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Table 2 : Prevalence of Symptoms of CKD among the Study Population during the Period of One Week by their Stage in the CKD Disease

From: Symptom burden in chronic kidney disease; a population based cross sectional study

Symptom

Early stage

(N = 259)

Stage 4

(N = 629)

Stage 5 – Non dialysis

(N = 153)

Stage 5 – Dialysis

(N = 38)

n (%)

95% CI

n (%)

95% CI

n (%)

95% CI

n (%)

95% CI

Loss of appetite

150 (57.9)

51.9–63.9

410 (65.2)

61.5–68.9

104 (68.0)

60.6–75.4

32 (84.2)

72.6–95.8

Nausea

77 (29.7)

24.1–35.3

206 (32.8)

29.1–36.5

67 (43.7)

35.8–51.6

22 (57.9)

42.2–73.6

Vomiting

25 (9.6)

6.0–13.2

77 (12.2)

9.6–14.8

38 (24.8)

18.0–31.6

10 (26.3)

12.3–40.3

Diarrhea

10 (3.8)

1.5–6.1

35 (5.5)

3.7–7.3

13 (8.5)

4.1–12.9

06 (15.8)

4.2–27.4

Lethargy

133 (51.4)

45.3–57.5

360 (57.2)

53.3–61.1

95 (62.1)

54.4–69.8

32 (84.2)

72.6–95.8

Changes in skin color

29 (11.2)

7.4–15.0

89 (14.1)

11.4–16.8

48 (31.4)

24.0–38.8

22 (57.9)

42.2–73.6

Swelling of arms or legs

104 (40.2)

34.2–46.2

321 (51.0)

47.1–54.9

115 (75.2)

68.4–82.0

21 (81.6)

69.3–93.9

Difficulty in breathing

146 (44.8)

38.7–50.9

338 (55.3)

51.4–59.2

100 (78.4)

71.9–84.9

32 (84.2)

72.6–95.8

Hiccups

29 (11.2)

7.4–15.0

105 (16.7)

13.8–19.6

31 (20.3)

13.9–26.7

13 (34.2)

19.1–49.3

Difficulty keeping legs still

15 (5.8)

3.0–8.6

80 (12.7)

10.1–15.3

126 (82.3)

76.3–88.3

38 (100.0)

100.0–100

Numbness/tingling of hands and feet

46 (17.7)

13.1–22.3

173 (27.5)

24.2–31.2

105 (68.6)

61.2–76.0

29 (76.3)

31.4–63.2

Lack of energy

178 (68.7)

63.1–74.3

467 (74.2)

70.8–77.6

138 (90.2)

85.5–94.9

35 (92.1)

83.5–100.0

Trouble with memory

150 (57.9)

51.9–63.9

369 (58.7)

54.9–62.5

106 (69.3)

62.9–75.7

27 (71.1)

54.7–87.5

Weight loss

84 (32.4)

26.7–38.1

203 (32.3)

28.6–36.0

49 (32.0)

24.2–39.8

23 (60.5)

42.4–78.6

Bone/joint pain

222 (85.7)

81.4–90.0

550 (87.4)

84.8–90.0

139 (90.8)

82.9–98.7

37 (97.4)

93.4–100.0

Muscle cramps

185 (71.4)

65.9–76.9

493 (78.4)

75.2–81.6

121 (79.1)

71.3–86.9

35 (92.1)

85.3–98.9

Difficulty concentrating

146 (56.4)

50.4–62.4

379 (60.3)

56.5–64.1

90 (58.8)

51.1–66.5

31 (81.6)

69.5–93.7

Dry skin

100 (38.6)

32.7–44.5

289 (45.9)

42.0–49.8

87 (55.6)

48.5–62.7

23 (60.5)

41.9–79.1

Itching

106 (40.9)

34.9–46.9

280 (44.5)

40.6–48.4

88 (57.5)

51.3–63.7

22 (57.9)

37.8–78.0

Feeling sad

161 (62.2)

56.3–68.1

374 (59.5)

55.7–63.3

93 (60.8)

52.9–68.7

30 (78.9)

67.3–90.5

Difficulty sleeping

167 (64.5)

58.7–70.3

431 (68.5)

64.9–72.1

110 (71.9)

64.0–79.8

33 (86.8)

77.6–96.0

Feeling irritable

200 (77.2)

72.1–82.3

486 (77.3)

74.0–80.6

124 (81.0)

73.3–88.7

36 (94.7)

88.8–100.0

Loss/ decreased libido

113 (43.6)

37.6–49.6

272 (43.2)

39.3–47.1

70 (45.8)

37.9–53.7

24 (63.2)

47.9–78.5

Impotence

109 (42.1)

36.1–48.1

270 (42.9)

39.0–46.8

70 (45.8)

37.9–53.7

24 (63.2)

47.9–78.5

Heartburn

139 (53.7)

47.6–59.8

342 (54.4)

50.5–58.3

93 (60.8)

53.1–68.5

25 (65.8)

50.7–80.9

  1. *CKD stage was not available in 39 study units