Blood volume-monitored regulation of ultrafiltration to decrease the dry weight in fluid-overloaded hemodialysis patients: a randomized controlled trial

Table 7 Ultrafiltration rates, blood flow rates and dialysis time

				p-value⁺
	CONV	UTR	UCR	CONV vs UTR	CONV vs UCR	UTR vs UCR	Overall
N participants with dry weight reduction	12	17	14
Average UF rate during study [mL/h]	429 ± 184	583 ± 218	745 ± 200	0.06	0.001	0.042	0.002
Average UF rate during study (ml/h/kg body weight)	6.5 ± 3.7	9.0 ± 3.9	11.5 ± 3.7	0.104	0.003	0.082	0.009
Average UF rate low during Intervention Phase [mL/h]	622 ± 149	479 ± 132	476 ± 124	0.018	0.018	0.955	0.020
Average UF rate low during Intervention Phase (ml/h/kg body weight)	8.9 ± 3.5	7.2 ± 2.2	7.6 ± 2.3	0.149	0.308	0.645	0.286
Average UF rate high during Intervention Phase [mL/h]	657 ± 186	1209 ± 292	873 ± 244	<0.01	0.008	0.004	<0.01
Average UF rate high during Intervention Phase (ml/h/kg body weight)	8.9 ± 3.5	18.2 ± 5.4	13.9 ± 5.4	<0.01	0.016	0.054	<0.01
BF rate throughout [mL/min]	290 ± 29	281 ± 37	278 ± 27				0.61
Dialysis time [h/session]	4.0 ± 0.4	3.9 ± 0.3	4.0 ± 0.6				0.90

CONV conventional hemodialysis, UTR ultrafiltration and temperature regulation, UCR ultrafiltration and dialysate conductivity regulation, N number, UF ultrafiltration, BF blood flow
Per protocol analysis. ⁺ P-values between groups determined by two-tailed t-test, and Mann-Whitney U test. Overall p-values determined by ANOVA

ISSN: 1471-2369