Skip to main content
Fig. 3 | BMC Nephrology

Fig. 3

From: Hemolytic uremic syndrome as the presenting manifestation of WT1 mutation and Denys-Drash syndrome: a case report

Fig. 3

Schematic depicting the location of the patient’s WT1 mutation. a The WT1 gene encodes a 10 exon mRNA transcript (Transcript ID: ENST00000448076). The patient harbored a c.1384C > T missense mutation in exon 9. b The result of this missense mutation is that the corresponding 449 amino acid WT1 protein (Uniprot ID: P19544) has a p.394R > W substitution that is located in the third Zinc finger domain. Pink rectangles represent low complexity regions. Protein schematic was generated using SMART [25]

Back to article page