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Fig. 2 | BMC Nephrology

Fig. 2

From: Long-term renal survival of γ3-heavy chain deposition disease: a case report

Fig. 2

Immunofluorescence staining shows moderate positivity for IgG (a) and C3 (b) within the mesangial nodules and in a linear deposition along the capillary walls. However, κ (c) and λ (d) are undetectable in the same glomerule. Original magnification 400×. e-h Immunofluorescence findings for IgG subclasses. Only IgG3 (g) is intensely positive in the mesangium area and along the glomerular and tubular basement membranes. Staining for IgG1 (e), IgG2 (f), and IgG4 (h) was absolutely negative in the same specimen. Original magnification 100×

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