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Table 1 Baseline characteristics of the Derivation cohort by GFR status at follow-up

From: Risk scores to predict decreased glomerular filtration rate at 10 years in an Asian general population

 

All

Decreased GFR (n = 271)

Preserved GFR (n = 2915)

P value

Age, years

51.3 ± 7.4

55.1 ± 8.2

50.9 ± 7.2

<0.001

Female sex, %

29.5 (940)

15.5 (42)

30.8 (898)

<0.001

Diabetes, %

7.8 (244)

17.7 (47)

6.9 (197)

<0.001

Systolic blood pressure, mm Hg

122.3 ± 17.2

132.4 ± 20.8

121.4 ± 16.5

<0.001

Waist circumference, cm.

86.3 ± 9.6

89.9 ± 9.1

85.9 ± 9.6

<0.001

Hypertension, %

15.9 (495)

31.6 (85)

14.4 (410)

<0.001

High density lipoprotein cholesterol, mg/dL

54.6 ± 14.7

52.2 ± 13.3

54.8 ± 14.8

0.005

Triglycerides, mg/dL

146.2 ± 99.8

162.2 ± 99.9

144.7 ± 99.7

0.006

Total cholesterol, mg/dL

237.0 ± 41.8

236.1 ± 45.2

237.1 ± 41.5

0.704

Blood sugar, mg/dL

99.5 ± 25.5

109.5 ± 37.6

98.6 ± 23.9

<0.001

Body mass index, kg/m2

24.3 ± 3.5

25.2 ± 3.4

24.3 ± 3.5

<0.001

 BMI ≥ 30 kg/m2, %

7.1 (222)

9.0 (24)

6.9 (198)

0.197

 BMI ≥ 25 kg/m2, %

44.5 (1401)

57.7 (154)

43.3 (1247)

<0.001

Current smoking, %

16.2 (509)

17.5 (47)

16.1 (462)

<0.001

Cardiovascular disease, %a

1.3 (42)

2.6 (7)

1.2 (35)

0.056

Serum creatinine, mg/dl

1.00 ± 0.18

1.10 ± 0.18

0.99 ± 0.18

<0.001

Estimate glomerular filtration rate, mL/min/1.73m2

81.8 ± 12.6

73.1 ± 12.3

82.6 ± 12.4

<0.001

Categorical eGFR, mL/min/1.73m2

   

<0.001

 60–74 mL/min/1.73m2, %

27.3 (870)

68.3 (185)

30.8 (898)

 

 75–89 mL/min/1.73m2, %

38.7 (1233)

21.8 (59)

40.3 (1174)

 

 90–119 mL/min/1.73m2, %

34.0 (1083)

10.0 (27)

28.9 (843)

 

Dipstick proteinuria, %

15.9 (187)

25.2 (33)

14.8 (154)

0.002

Serum Uric acid, mg/dL

5.6 ± 1.4

6.4 ± 1.5

5.6 ± 1.4

<0.001

Hemoglobin, mg/dL

14.4 ± 1.5

14.6 ± 1.4

14.4 ± 1.5

0.046

  1. Decreased GFR (eGFR < 60), Preserved (eGFR ≥ 60) at follow-up in 2012–2013
  2. Data represented as mean ± SD or percent (number)
  3. aIncludes peripheral vascular disease, heart muscle, heart attack, stroke