Risk scores to predict decreased glomerular filtration rate at 10 years in an Asian general population

BMC Nephrology

Table 2 Risk factors for developing Decreased GFR at 10 years

Model	Covariate	Odds ratio (95% CI)	P-Value
1	Age (per year)	1.06 (1.04–1.08)	<.001
	Sex (male)	1.83 (1.27–2.63)	.001
	Systolic blood pressure (per mm/Hg)	1.02 (1.02–1.03)	<.001
	Waist circumference (per cm)	1.02 (1.01–1.37)	.041
	Diabetic mellitus (Yes/No)	1.75 (1.20–2.55)	.004
2	Age (per year)	1.03 (1.01–1.05)	.002
	Sex (male)	1.44 (1.00–2.08)	.049
	Systolic blood pressure (per mm/Hg)	1.02 (1.02–1.03)	<.001
	Waist circumference (per cm)	1.01 (1.00–1.03)	.113
	Diabetic mellitus	2.50 (1.74–3.60)	<.001
	GFR (per ml/min/1.73m²)	0.93 (0.92–0.94)	<.001
3	Age (per year)	1.03 (1.01–1.05)	.001
	Sex (male)	1.51 (1.04–2.20)	.032
	Systolic blood pressure (per mm/hg)	1.02 (1.01–1.03)	<.001
	Waist circumference (per cm)	1.01 (0.99–1.03)	.220
	Diabetic mellitus	2.60 (1.80–3.74)	<.001
	GFR (per ml/min/1.73m²)	0.93 (0.92–0.95)	<.001
	Uric acid^a	1.60 (1.12–2.25)	.009
	Hemoglobin^b	2.04 (1.22–3.41)	.007
	HDL-cholesterol^c	1.10 (0.77–1.57)	.607

Decreased GFR defined as new cases with eGFR < 60 at follow-up by the CKD-EPI formula
^adefined as uric acid >6 for female and >7 for male
^bdefined as hemoglobin < 12 for female and <13 for male
^cdefined as HDL-cholesterol < 40 for male and <50 for female

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