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Table 1 Clinical characteristics and the Oxford IgAN classification at the time of renal biopsy in 403 patients with IgAN

From: Increased C4 and decreased C3 levels are associated with a poor prognosis in patients with immunoglobulin A nephropathy: a retrospective study

Clinical characteristics Oxford classification (n [%])
Female (n [%]) 223 (55.3) Mesangial hypercellularity
Age (years, mean [SD]) 37.1 (11.8) M0 280 (69.4)
Systolic blood pressure (mmHg, mean [SD]) 129.7 (18.1) M1 121 (30.0)
Diastolic blood pressure (mmHg, mean [SD]) 81.4 (12.1) Endocapillary hypercellularity
MAP (mmHg, mean [SD]) 97.6 (13.4) E0 274 (68)
Hemoglobin (g/L, mean [SD]) 125.9 (1 9.0) E1 127 (31.5)
Serum creatinine (μmol/L, mean [SD]) 87.7 (46.3) Segmental glomerulosclerosis
eGFR (ml/min/1.73 m2, mean [SD]) 94.5 (30.9) S0 101 (25.1)
24 h urinary protein (g/L, median [IQR]) 1.2 (1.5) S1 300 (74.4)
Serum C3 (g/L, mean [SD]) 0.95 (0.19) Tubular atrophy/interstitial fibrosis
Serum C4 (g/L, mean [SD]) 0.22 (0.07) T0 294 (73.0)
   T1 84 (20.8)
   T2 23 (5.7)
  1. SD standard deviation, IQR interquartile range