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Table 3 Univariate and Multivariate Cox proportional-hazard regression analyses for the risk factors of poor outcome

From: Increased C4 and decreased C3 levels are associated with a poor prognosis in patients with immunoglobulin A nephropathy: a retrospective study

Factors Univariate Analysis Multivariate Analysis
HR (95%CI) p-value HR (95%CI) p-value
Age (Year) 0.5 (0.3-0.8) 0.003 0.3 (0.2-0.6) <0.001
Gender   0.32   -
 Female 1   -  
 Male 1.4 (0.7-2.6)   -  
Systolic blood pressure (mmHg) 1.5 (1-2.2) 0.04 1.2 (0.6-2.3) 0.52
Diastolic blood pressure (mmHg) 1.5 (1-2.2) 0.05 1.4 (0.7-2.6) 0.32
24 h urinary protein (g/L) 1.4 (1.2-1.6) <0.001 1.4 (1.1-1.7) 0.003
Serum C3 (g/L) 0.6 (0.4-0.9) 0.03 0.4 (0.2-0.6) <0.001
Serum C4 (g/L) 1.5 (1-2.2) 0.03 2.4 (1.6-3.8) <0.001
Immunosuppressive therapy   0.04   <0.001
 GS group 1   1  
 non-GS group 2.0 (1.1-4.0)   4.0 (1.8-8.8)  
  1. HR hazard ratio, CI confidence interval