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Table 3 Univariate and Multivariate Cox proportional-hazard regression analyses for the risk factors of poor outcome

From: Increased C4 and decreased C3 levels are associated with a poor prognosis in patients with immunoglobulin A nephropathy: a retrospective study

Factors

Univariate Analysis

Multivariate Analysis

HR (95%CI)

p-value

HR (95%CI)

p-value

Age (Year)

0.5 (0.3-0.8)

0.003

0.3 (0.2-0.6)

<0.001

Gender

 

0.32

 

-

 Female

1

 

-

 

 Male

1.4 (0.7-2.6)

 

-

 

Systolic blood pressure (mmHg)

1.5 (1-2.2)

0.04

1.2 (0.6-2.3)

0.52

Diastolic blood pressure (mmHg)

1.5 (1-2.2)

0.05

1.4 (0.7-2.6)

0.32

24 h urinary protein (g/L)

1.4 (1.2-1.6)

<0.001

1.4 (1.1-1.7)

0.003

Serum C3 (g/L)

0.6 (0.4-0.9)

0.03

0.4 (0.2-0.6)

<0.001

Serum C4 (g/L)

1.5 (1-2.2)

0.03

2.4 (1.6-3.8)

<0.001

Immunosuppressive therapy

 

0.04

 

<0.001

 GS group

1

 

1

 

 non-GS group

2.0 (1.1-4.0)

 

4.0 (1.8-8.8)

 
  1. HR hazard ratio, CI confidence interval