Variable | Total n = 279,956 | RLS n = 372 | NSD n = 279,584 | P |
---|---|---|---|---|
Incidence age, years | 62.05 ± 15.39 | 64.22 ± 15.64 | 62.04 ± 15.39 | 0.007 |
Gender | Â | Â | Â | 0.2 |
 Female | 43.72 (122,400) | 47.3 (176) | 43.7 (122,224) |  |
 Male | 56.28 (157,556) | 52.7 (196) | 56.3 (157,360) |  |
Race | Â | Â | Â | <.0001 |
 White | 64.38 (180,239) | 86.29 (321) | 64.35 (179,918) |  |
 Black | 29.93 (83,782) | 11.56 (43) | 29.95 (83,739) |  |
 Asian | 3.32 (9282) | 1.34 (5) | 3.32 (9277) |  |
 Native American | 1.08 (3026) | 0.27 (1) | 1.08 (3025) |  |
 Other/Unknown | 1.3 (3627) | 0.54 (2) | 1.3 (3625) |  |
Ethnicity | Â | Â | Â | 0.002 |
 Non-Hispanic/Latino | 85.68 (239,880) | 91.4 (340) | 85.68 (239,540) |  |
 Hispanic/Latino | 14.32 (40,076) | 8.6 (32) | 14.32 (40,044) |  |
Vascular access type | Â | Â | Â | 0.0002 |
 AV Fistula | 14.61 (40,902) | 23.12 (86) | 14.6 (40,816) |  |
 Graft | 3.95 (11,058) | 4.3 (16) | 3.95 (11,042) |  |
 Catheter | 80.28 (224,739) | 71.77 (267) | 80.29 (224,472) |  |
 Other/Unknown | 1.16 (3257) | 0.81 (3) | 1.16 (3254) |  |
Body mass index (kg/m2)f | 28.74 ± 7.71 | 28.98 ± 7.57 | 28.74 ± 7.71 | 0.5 |
Serum creatinine (mg/dl)f | 6.58 ± 3.46 | 6.64 ± 3.74 | 6.58 ± 3.46 | 0.8 |
Serum albumin (g/dl)f | 3.11 ± 0.71 | 3.32 ± 0.64 | 3.11 ± 0.71 | <.0001 |
Anemiaa | 8.37 (23,432) | 11.83 (44) | 8.37 (23,388) | 0.02 |
Cardiovascular | ||||
 Coronary artery diseaseb | 21.09 (59,054) | 17.2 (64) | 21.1 (58,990) | 0.07 |
 Congestive heart failure | 32.18 (90,088) | 26.34 (98) | 32.19 (89,990) | 0.02 |
 Cerebrovascular disease | 9.4 (26,329) | 8.06 (30) | 9.41 (26,299) | 0.4 |
 Peripheral vascular disease | 14.04 (39,301) | 10.22 (38) | 14.04 (39,263) | 0.03 |
 Hypertension | 84.92 (237,737) | 83.6 (311) | 84.92 (237,426) | 0.5 |
Other | ||||
 Diabetes | 52.78 (147,771) | 38.98 (145) | 52.8 (147,626) | <.0001 |
 Cancer | 6.81 (19,065) | 5.91 (22) | 6.81 (19,043) | 0.5 |
Sleep disorders | ||||
 Any sleep disorder | 0.13 (372) | 100.0 (372) | 0 (0) | <.0001 |
 Restless legs syndrome | 0.13 (372) | 100.0 (372) | 0 (0) | <.0001 |
 Obstructive sleep apnea | 0.01 (17) | 4.57 (17) | 0 (0) | <.0001 |
Psychological disorders | ||||
 Major depressive disorder | 0.37 (1030) | 1.61 (6) | 0.37 (1024) | <.0001 |
 Dysthymic disorder | 0.26 (727) | 2.15 (8) | 0.26 (719) | <.0001 |
 Anxiety | 0.6 (1691) | 4.03 (15) | 0.6 (1676) | <.0001 |
 Adjustment disorder | 0.03 (81) | 0.27 (1) | 0.03 (80) | 0.1 |
 Depressionc | 0.65 (1829) | 4.03 (15) | 0.65 (1814) | <.0001 |
 Minor depressive disorderd | 0.29 (808) | 2.42 (9) | 0.29 (799) | <.0001 |
 Psychological disordere | 1.24 (3459) | 8.06 (30) | 1.23 (3429) | <.0001 |
Tobacco dependence | 6.39 (17,887) | 8.87 (33) | 6.39 (17,854) | 0.05 |
Alcohol dependence | 1.57 (4384) | 0.81 (3) | 1.57 (4381) | 0.2 |
Drug dependence | 1.55 (4339) | 1.08 (4) | 1.55 (4335) | 0.5 |