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Table 2 Serum FLC parameters to differentiate patients with and without myeloma in patients presenting with AKI

From: Multiple myeloma can be accurately diagnosed in acute kidney injury patients using a rapid serum free light chain test

 

AUC

Best cut-off

Sensitivity

Specificity

Ratio: myeloma κ

1.0

(95% CI 1–1, p < .001)

2.02

100%

100%

Ratio: myeloma λ

1.0

(95% CI 1–1, p < .001)

0.14

100%

100%

FLC sum

0.97

(95% CI .94–.1.0, p < .001)

528 mg/L

89%

94%

dFLC

0.99

(95% CI .97–1.0, p < .001)

399 mg/L

91%

100%

  1. Data is shown ROC analyses for the κ:λ ratio, FLC sum and FLC difference (dFLC) measured using Seralite®. Area under curve (AUC, with 95% confidence intervals [CI]) was calculated and the best cut-off point identified with associated sensitivity and specificity are reported for each FLC parameter