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Table 3 The Characteristics at the time of renal replacement therapy initiation in studies included in Meta-analysis

From: A comparison of early versus late initiation of renal replacement therapy for acute kidney injury in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials

Author

Modality

Creatinine (mg/d L)

Urine output (ml/24 h)

APACHE II score

SOFA score

Early

Late

Early

Late

Early

Late

Early

Late

Bouman

CVVH

NR

NR

NR

NR

EHV:23.5 (8.4)

ELV:21.7 (5.5)

LLV:23.6 (8.3)

EHV:10.3 (2.8)

ELV:10.1 (2.2)

LLV:10.6 (1.9)

Durmaz

IHD

3.1 (1.0)

4.3 (1.1)

NR

NR

NR

NR

NR

NR

Sugahara

CVVH

2.9 (0.2)

3.0 (0.2)

29 (1)a

18 (1)a

19 (2)

18 (3)

NR

NR

Payen

CVVH

2.1 (1.1)

2.1 (1.3)

1543 (209)

1491 (242)

NR

NR

NR

NR

Jamale

IHD

7.4 (5.3)

10.4 (3.3)

429 (388)

376 (350)

NR

NR

7.6 (3.3)

8.2 (3.1)

Combes

CVVH

1.7 (0.9)

1.8 (0.9)

NR

NR

NR

NR

11.5 (2.8)

12 (2.9)

Wald

IHD/CVVH/SLED

3.7 (1.4)

4.6 (2.2)

400 (211–568)

265 (80–755)

NR

NR

12 (3.3)

11.9 (2)

Gaudry

IHD/CVVH

3.3 (1.4)

5.3 (2.3)

NR

150 (50–600)

NR

NR

10.9 (3.2)

10.8 (3.1)

Zarbock

CVVH

1.9 (0.6)

2.4 (1)

445 (175–807.5)

270 (112.5–670)

30.6 (7.5)

32.7 (8.8)

15.6 (2.3)

16 (2.3)

  1. Abbreviations: NR not reported, APACHE acute physiology and chronic health evaluation, SOFA sequential organ failure assessment, EHV early high volume, ELV early low volume, LLV late low volume, CVVH continuous venovenous hemofiltration, IHD intermittent hemodialysis, SLED sustained low-efficiency dialysis
  2. aSugahar reported urine output by ml/h