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Table 3 The Characteristics at the time of renal replacement therapy initiation in studies included in Meta-analysis

From: A comparison of early versus late initiation of renal replacement therapy for acute kidney injury in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials

Author Modality Creatinine (mg/d L) Urine output (ml/24 h) APACHE II score SOFA score
Early Late Early Late Early Late Early Late
Bouman CVVH NR NR NR NR EHV:23.5 (8.4)
ELV:21.7 (5.5)
LLV:23.6 (8.3) EHV:10.3 (2.8)
ELV:10.1 (2.2)
LLV:10.6 (1.9)
Durmaz IHD 3.1 (1.0) 4.3 (1.1) NR NR NR NR NR NR
Sugahara CVVH 2.9 (0.2) 3.0 (0.2) 29 (1)a 18 (1)a 19 (2) 18 (3) NR NR
Payen CVVH 2.1 (1.1) 2.1 (1.3) 1543 (209) 1491 (242) NR NR NR NR
Jamale IHD 7.4 (5.3) 10.4 (3.3) 429 (388) 376 (350) NR NR 7.6 (3.3) 8.2 (3.1)
Combes CVVH 1.7 (0.9) 1.8 (0.9) NR NR NR NR 11.5 (2.8) 12 (2.9)
Wald IHD/CVVH/SLED 3.7 (1.4) 4.6 (2.2) 400 (211–568) 265 (80–755) NR NR 12 (3.3) 11.9 (2)
Gaudry IHD/CVVH 3.3 (1.4) 5.3 (2.3) NR 150 (50–600) NR NR 10.9 (3.2) 10.8 (3.1)
Zarbock CVVH 1.9 (0.6) 2.4 (1) 445 (175–807.5) 270 (112.5–670) 30.6 (7.5) 32.7 (8.8) 15.6 (2.3) 16 (2.3)
  1. Abbreviations: NR not reported, APACHE acute physiology and chronic health evaluation, SOFA sequential organ failure assessment, EHV early high volume, ELV early low volume, LLV late low volume, CVVH continuous venovenous hemofiltration, IHD intermittent hemodialysis, SLED sustained low-efficiency dialysis
  2. aSugahar reported urine output by ml/h