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Table 6 RRT-related Complications of Studies Included in Meta-analysis

From: A comparison of early versus late initiation of renal replacement therapy for acute kidney injury in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials

Outcomes Study No. No of patients Risk Difference (95% CI) P for Effect I2 P for Model
hemorrhage 6 1458 0.00(−0.02, 0.01) 0.89 0% 0.73
thrombocytopenia 3 949 0.05(−0.04, 0.14) 0.25 60% 0.08
thrombosis 2 700 −0.01(−0.04, 0.02) 0.40 0% 0.58
hypokalemia 3 924 0.00(−0.08, 0.07) 0.89 61% 0.08
hypophosphatemia 3 924 0.11(−0.09, 0.31) 0.28 92% <0.0001
hyperkalemia 2 843 −0.01(−0.04, 0.02) 0.41 0% 0.56
RRT-associated arrhythmia 3 920 −0.02(−0.08, 0.04) 0.48 58% 0.09
RRT-associated seizure 3 525 0.00(−0.01, 0.01) 0.85 0% 0.55
hypothermia 2 843 0.01(−0.01, 0.04) 0.28 0% 0.62
catheter infection 4 1014 0.01(−0.02, 0.04) 0.36 31% 0.23
hypotension during RRT 3 652 0.02(−0.02, 0.06) 0.37 37% 0.21
  1. Abbreviations: RRT renal replacement therapy