Table 1 General characteristics and factors associated with ESA prescription: univariate analysis (Student T-test test or chi square test as appropriate, n = 240 patients)
Total population (n = 240) | Patients without ESA (n = 71) | Patients with ESA (n = 169) | p-value | |
|---|---|---|---|---|
Age (years) | 67.6 ± 16.0 | 68.6 ± 14.8 | 67.3 ± 16.6 | 0.56 |
Male gender | 55.4% | 62.0% | 52.7% | 0.19 |
Time on dialysis (months) | 82 ± 121 | 80 ± 89 | 83 ± 133 | 0.87 |
Diabetes mellitus | 42.5% | 43.7% | 42.0% | 0.81 |
Dry weight (kg) | 69.6 ± 14.9 | 71.4 ± 15.6 | 68.9 ± 14.6 | 0.23 |
ADPKD | 4.6% | 4.2% | 4.7% | 1.00 |
White cell count (G/L) | 7.01 ± 4.62 | 6.55 ± 2.05 | 7.21 ± 5.34 | 0.31 |
Lymphocytes (G/L) | 1.28 ± 0.58 | 1.34 ± 0.62 | 1.25 ± 0.57 | 0.27 |
Hemoglobin (g/dL) | 10.8 ± 1.2 | 11.4 ± 1.1 | 10.6 ± 1.2 | <0.001 |
MCV (fl) | 94 ± 8 | 93 ± 6 | 95 ± 8 | 0.33 |
Platelet count (G/L) | 203 ± 79 | 187 ± 70 | 209 ± 82 | 0.06 |
TSAT (%) | 25.5 ± 13.5 | 31.1 ± 16.3 | 23.1 ± 11.5 | <0.001 |
Ferritin (ng/mL) | 530 ± 520 | 577 ± 640 | 510 ± 461 | 0.36 |
Albumin (g/L) | 37.7 ± 5.3 | 37.9 ± 4.8 | 37.6 ± 5.5 | 0.65 |
β2 microglobulin (mg/L) | 26.6 ± 7.4 | 27.4 ± 7.9 | 26.4 ± 7.1 | 0.40 |
Parathormone (pg/mL) | 256 ± 318 | 263 ± 313 | 252 ± 119 | 0.82 |
Predialysis creatinine (μmol/L) | 732 ± 253 | 748 ± 273 | 725 ± 244 | 0.52 |
Predialysis urea (mmol/L) | 20.7 ± 6.6 | 20.4 ± 5.9 | 20.8 ± 6.8 | 0.64 |
C-reactive protein (mg/L) | 20.0 ± 43.5 | 16.6 ± 37.8 | 21.4 ± 45.7 | 0.44 |
IAA (μmol/L) | 4.73 ± 4.79 | 4.79 ± 5.06 | 4.71 ± 4.69 | 0.91 |
IS (μmol/L) | 93.3 ± 51.5 | 91.1 ± 53.0 | 94.2 ± 51.0 | 0.67 |
PCS(μmol/L) | 158 ± 99 | 165 ± 99 | 154 ± 99 | 0.44 |
ESA dose (μg/w) | - | - | 53.9 ± 50.0 | - |
IV iron medication (%) | 61.7% | 52.1% | 65.7% | 0.04 |
Iron dose (mg/mo) | 232 ± 267 | 173 ± 200 | 257 ± 288 | 0.03 |
Vascular access | ||||
Native AV fistula | 63.3% | 54.9% | 66.9% | 0.17 |
AV graft | 16.7% | 18.3% | 16.0% | |
Catheter | 20.0% | 26.8% | 17.2% | |
HDF (%) | 41.7% | 53.5% | 36.7% | 0.02 |
Kt/V | 1.51 ± 0.31 | 1.51 ± 0.26 | 1.51 ± 0.32 | 0.98 |