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Table 1 Clinical characteristics

From: Urine neutrophil gelatinase-associated lipocalin to predict renal response after induction therapy in active lupus nephritis

Variables N (%) or mean ± SD Median with IQR
Female (N, %) 66 (97.1%)  
Age (years) 31.7 ± 10.0 32 (23, 38)
Body weight (kg) 54.7 ± 14.9 50.9 (45.9, 62)
Body mass index 20.1 ± 3.9  
Duration of SLE (years) 6.3 ± 6.3 4 (2, 8.5)
Systolic blood pressure (mmHg) 126.7 ± 24.3 128 (119, 138.5)
Diastolic blood pressure (mmHg) 79.4 ± 19.2 78.5 (70, 92)
Systemic organ involvements (N, %)
 Arthritis 14 (20.6%)  
 Cutaneous lupus 14 (20.6%)  
 Hematologic involvement 8 (11.8%)  
 Serositis 4 (5.9%)  
 Neurological involvement 1 (1.5%)  
Baseline SLEDAI score 10.8 ± 3.3 10 (8, 12)
Baseline Renal SLEDAI score 7.0 ± 2.9 8 (4, 8)
ISN/RPS class (N, %)
 Class III 5 (7.4%)  
 Class IV 49 (72.1%)  
 Class III + V 4 (5.9%)  
 Class IV + V 10 (14.7%)  
Renal activity index 8.5 ± 2.9 8 (6, 11.5)
Renal chronicity index 1.9 ± 1.7 2 (0, 3)
Immunosuppressive agents (N, %)
 Induction with high cyclophosphamide 37 (62.7%)  
 Induction with mycophenolate 22 (37.3%)  
 Mean dose of mycophenolate (mg/day) 29.6 ± 17.1 30 (20, 35)
 Prednisolone 67 (98.5%)  
 Hydroxychloroquine 32 (47.1%)  
Anti-hypertensive and lipid lowering agents (N, %)
 RAAS blockers 51 (75%)  
 Calcium channel blockers 10 (14.7%)  
 Diuretics 28 (41.2%)  
 Statins 43 (63.2%)  
Laboratory data
 Positive ANA (%) 67 (98.5%)  
 Positive anti-dsDNA (%) 57 (83.8%)  
 Low complement component 3 (C3) (%) 31 (60.8%)  
 Serum complement component C3 levels (g/L) 1.2 ± 1.8 0.7 (0.4, 1.1)
 Hematocrit (%) 26.5 ± 11.2 30 (13.7, 34.6)
 Serum albumin (g/dL) 2.7 ± 0.9 3 (2, 3.2)
 Serum creatinine (mg/dL) 0.9 ± 0.5 0.8 (0.7, 1.1)
 Estimated GFR (mL/min/1.73 m2) 89.6 ± 33.7 89.4 (63.7, 116.8)
 UPCR (g/g creatinine) 5.9 ± 4.8 4.8 (2.5, 6.9)
  1. Abbreviations ANA antinuclear antibody, Anti-dsDNA anti-double-stranded DNA antibody, ISN/RPS International Society of Nephrology/Renal Pathology Society, GFR glomerular filtration rate, RAAS renin angiotensin aldosterone system, SLEDAI systemic lupus erythematosus disease activity index, UPCR urine protein creatinine ratio
  2. Values for categorical variables are given as number (percentage); values for continuous variables, as mean ± standard deviation or median [interquartile range]