Urine neutrophil gelatinase-associated lipocalin to predict renal response after induction therapy in active lupus nephritis

Table 3 Correlation of urine NGAL with other parameters at baseline in active lupus nephritis

	Urine NGAL (ng/mL)		Urine NGAL (ng/mgCr)
	Spearman’s rho	p-value	Spearman’s rho	p-value
Age (years)	0.089	0.473	0.001	0.992
ACEIs or ARBs	−0.018	0.883	0.007	0.955
Diuretics	−0.059	0.635	−0.116	0.344
Systolic blood pressure (mmHg)	0.360	0.003	0.198	0.105
Diastolic blood pressure (mmHg)	0.359	0.003	0.045	0.715
SLEDAI score	−0.079	0.523	0.034	0.780
Renal SLEDAI score	0.069	0.576	0.086	0.485
Positive anti-dsDNA antibody	0.040	0.743	−0.171	0.163
Serum complement C3 levels (g/L)	0.273	0.053	0.038	0.793
Low complement C3	−0.389	0.005	−0.130	0.365
Serum creatinine (mg/dL)	0.231	0.058	0.344	0.004
UPCI (g/g creatinine)	0.280	0.021	−0.014	0.910
Estimated GFR (mL/min/1.73 m²)	−0.262	0.031	−0.270	0.026

Abbreviations ACEI, angiotensin converting enzyme inhibitor, Anti-dsDNA anti-double-stranded DNA antibody, ARBs, angiotensin receptor blockers, GFR glomerular filtration rate, RAAS renin angiotensin aldosterone system, SLEDAI systemic lupus erythematosus disease activity index, UPCR urine protein creatinine ratio

ISSN: 1471-2369