Overall
|
8
|
0.041
|
52.2
|
Random-effect
|
1.254
|
1.046–1.503
|
0.015
| |
CKD stage
| | | | | | | |
0.79
|
CKD stage 3–5
|
3
|
0.75
|
0.0%
|
Fix-effect
|
1.245
|
1.119–1.385
|
0.000
| |
CKD stage 5D (hemodialysis)
|
4
|
0.030
|
66.4%
|
Random-effect
|
1.315
|
0.885–1.954
|
0.176
| |
Transplant
|
1
|
NA
|
NA
|
NA
|
7.17
|
1.4–76.4
|
NA
| |
Adjustment for confounding factors
| | | | | | | | |
Unadjusted
|
1
|
NA
|
NA
|
NA
|
7.17
|
1.4–76.4
|
NA
| |
Adjusted
|
7
|
0.072
|
48.2%
|
Fixed-effect
|
1.194
|
1.091–1.306
|
0.016
|
0.77
|
Adjusted for smoking and other variables
|
6
|
0.058
|
53.3%
|
Random-effect
|
1.209
|
1.016–1.438
|
0.032
| |
Adjusted for diabetes and other variables
|
6
|
0.093
|
47.1%
|
Fixed-effect
|
1.175
|
1.071–1.288
|
0.001
| |
Adjusted for diabetes, hypertension and other variables
|
4
|
0.664
|
0.0%
|
Fixed-effect
|
1.264
|
1.137–1.404
|
0.000
| |
Study duration
| | | | | | | |
0.14
|
Short (< 5 years)
|
3
|
0.029
|
71.9%
|
Random-effect
|
1.116
|
0.855–1.457
|
0.418
| |
Long (≥ 5 years)
|
5
|
0.448
|
0.0%
|
Fixed-effect
|
1.429
|
1.173–1.742
|
0.000
| |
Diagnostic criteria for periodontal disease
| | | | | | | |
0.23
|
PPD, CALs
|
5
|
0.838
|
0%
|
Fixed-effect
|
1.422
|
1.171–1.727
|
0.000
| |
CPITN
|
3
|
0.009
|
78.8%
|
Random-effect
|
1.125
|
0.812–1.559
|
0.478
| |
Regions
| | | | | | | |
0.99
|
Asian countries
|
2
|
0.227
|
31.6%
|
Fixed-effect
|
1.257
|
1.123–1.407
|
0.000
| |
European countries and USA
|
6
|
0.045
|
55.8%
|
Random-effect
|
1.259
|
0.927–1.710
|
0.14
| |
Reference population
| | | | | | | |
0.66
|
Healthy
|
4
|
0.752
|
0.0%
|
Fixed-effect
|
1.253
|
1.128–1.393
|
0.000
| |
Healthy to mild periodontal disease
|
4
|
0.012
|
72.4%
|
Random-effect
|
1.410
|
0.844–2.356
|
0.189
| |