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Table 2 Accuracy of CEUS compared to tissue diagnosis (primary analysis) and tissue diagnosis or follow-up imaging diagnosis (secondary analysis)a

From: Diagnostic accuracy of contrast-enhanced ultrasound for characterization of kidney lesions in patients with and without chronic kidney disease

 

Reader 1

Reader 2

Combined readers

Tissue diagnosis

(N = 23)

Tissue or follow-up imaging

(N = 44)

Tissue diagnosis

(N = 23)

Tissue or follow-up imaging

(N = 44)

Tissue diagnosis

(N = 23)

Tissue or follow-up imaging

(N = 44)

Sensitivity

90%

(78%, 100%)

[19/21]

91%

(80%, 100%)

[20/22]

100%

(100%, 100%)

[21/21]

100%

(100%, 100%)

[22/22]

95%

(83%, 99%)

96%

(84%, 99%)

Specificity

0%

(0%, 0%)

[0/2]

59%

(39%, 80%)

[13/22]

0%

(0%, 0%)

[0/2]

41%

(20%, 61%)

[9/22]

0%

(0%, 0%)

50%

(32%, 68%)

Overall Accuracy

83%

(67%, 98%)

[19/23]

75%

(62%, 88%)

[33/44]

91%

(80%, 100%)

[21/23]

70%

(57%, 84%)

[31/44]

87%

(69%, 95%)

73%

(59%, 83%)

  1. aResults presented as accuracy metrics (95% CI) and [positive or negative reads/total reads]. CEUS images were read by 2 independent readers. Results were considered per reader and as a combination of the 2 readers. For combined reader result, generalized estimating equations were used considering two readers’ values as repeated measurements (or responses)