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Fig. 1 | BMC Nephrology

Fig. 1

From: Effect of tolvaptan on renal handling of water and sodium, GFR and central hemodynamics in autosomal dominant polycystic kidney disease during inhibition of the nitric oxide system: a randomized, placebo-controlled, double blind, crossover study

Fig. 1

Effect of tolvaptan 60 mg during and after NO inhibition on GFR (51 Cr-EDTA-clearance) (a), UO (b), CH2O (c) and u-AQP2 (d) in ADPKD. Data are given as mean ± SEM or medians with 25th and 75th percentiles. General linear model (GLM) with repeated measures was performed for comparison within and between groups. Paired t-test was used for comparison between tolvaptan and placebo treatment during L-NMMA infusion period (90–150 min) and post infusion period (150–210 min)

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BMC Nephrology

ISSN: 1471-2369

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