Skip to main content
Fig. 7 | BMC Nephrology

Fig. 7

From: Indoleamine 2, 3-dioxygenase (IDO) increases during renal fibrogenesis and its inhibition potentiates TGF-β 1-induced epithelial to mesenchymal transition

Fig. 7

Scratch-wound migration of the MDCK cells. MDCK cells were seeded in 24-well plates and one scratch per well was carried out using a 10 μl pipette tip. After 11 hrs of migration, images were acquired. a Unstimulated MDCK cells (Control), (b) MDCK cells incubated with the IDO inhibitor 1-methyl-D-tryptophan (MT; 1 mM), (c) TGF-β 1-stimulated MDCK cells, and (d) TGF-β 1-stimulated MDCK cells treated with MT. TGF-β 1 promoted cell migration, and treatment with MT potentiated this effect (e). *p < 0.05 vs. Control and MT; # p < 0.05 vs. TGF-β 1

Back to article page

BMC Nephrology

ISSN: 1471-2369

Contact us