Fig. 1

Structure of the NAT2 gene and polymorphisms identified in our patient. The relative position of Exon 1, as well as the first (+1) and last (+873) positions of the open reading frame of Exon 2 are indicated. Vertical dotted lines show the positions of the single nucleotide polymorphisms identified in our patient. Haplotypes arising from the combinations of SNPs are shown in the table, with their associated acetylation activity