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Table 3 Clinical correlates of a) baseline abnormal PWV (≥10 m/s); b) baseline PWV and c) 12-month PWV in the entire study population

From: Progression of arterial stiffness is associated with changes in bone mineral markers in advanced CKD

  Unadjusted OR (95% CI) p Adjusted OR (95% CI)a p
a) Abnormal PWV (≥10 m/s) at baseline     
 Age (year) 1.12 (1.05–1.19) 0.001 1.14 (1.04–1.25) 0.004
 Diabetes 3.75 (1.33–10.56) 0.01 9.73 (1.37–69.0) 0.02
 Log FGF23 (pg/mL) 1.67 (1.14–2.43) 0.007 2.95 (1.04–8.34) 0.04
 Log PTH (pg/mL) 1.79 (1.03–3.08) 0.04 3.78 (1.31–10.9) 0.01
 eGFR(ml/min/1.73m2) 0.99 (0.97–1.00) 0.07 1.08 (1.03–1.15) 0.004
  Unadjusted Coefficient (95% CI) p Adjusted Coefficient (95% CI)a p
b) Baseline PWV     
 Age (year) 0.02 (0.01–0.02) <0.001 0.01 (0.01–0.02) <0.001
 Hypertension 0.25 (0.14–0.37) <0.001 0.24 (0.16–0.37) <0.001
 eGFR(ml/min/1.73m2) −0.002 (−0.003–0.0004) 0.06 0.006 (0.003–0.008) <0.001
 Log PTH (pg/mL) 0.08 (0.02–0.2) 0.02 0.13 (0.06–0.20) <0.001
 Log FGF23 (pg/mL) 0.06 (0.01–0.10) 0.01 0.05 (−0.003–0.11) 0.06
c) 12-month PWV     
 Baseline PWV (m/s) 0.73 (0.56–0.90) <0.001 0.49 (0.31–0.68) <0.001
 Diabetes 0.18 (0.08–0.29) 0.001 0.16 (0.06–0.26) 0.002
 uPCR (mg/mmol) 0.0007 (0.0003–0.001) 0.002 0.0006 (0.0001–0.001) 0.008
 Log FGF23 (pg/mL) 0.06 (0.03–0.10) 0.001 0.04 (0.005–0.07) 0.03
  1. aAdjusted for age, diabetes, hypertension, eGFR, uPCR, corrected calcium, phosphate, PTH and FGF23
  2. Abbreviations: CI confidence interval, eGFR estimated glomerular filtration rate, FGF23 fibroblast growth factor 23, OR odds ratio, PTH parathyroid hormone level, PWV pulse wave velocity, UPCR urinary protein-to-creatinine ratio