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Table 1 Minor allele frequencies of selected tagged single-nucleotide polymorphisms (SNPs) of the endothelin (EDN) gene family

From: Associations of genetic variants of endothelin with cardiovascular complications in patients with renal failure

Gene Position SNP Location Ref Alt AFR fre AMR fre ASN fre EUR fre TWB fre Our fre
EDN1 Ch6:12,289,406 rs3087459 5’UTR A C 0.19 0.14 0.20 0.20 0.23 0.17
Ch6:12,291,749 rs2248580 Intron C A 0.08 0.56 0.56 0.47 0.41 0.35
Ch6:12,292,539 rs2070699 Intron G T 0.05 0.46 0.56 0.47 0.49 0.43
Ch6:12,296,022 rs5370 Missense G T 0.14 0.17 0.28 0.21 0.31 0.23
Ch6:12,297,620 rs4714384 3’UTR T C 0.71 0.38 0.62 0.37 0.38 0.34
EDN2 Ch1:41,485,234 rs11572340 5’UTR C A 0.04 0.16 0.07 0.21 0.06 0.02
Ch1:41,484,301 rs11210278 Intron C T 0.01 0.11 0.33 0.19 0.30 0.29
Ch1:41,483,957 rs2759257 Intron A C 0.75 0.89 0.91 0.86 0.88 0.93
Ch1:41,478,124 rs11572377 3’UTR C G 0.01 0.01 0.08 0.02 0.09 0.05
EDN3 Ch20:59,303,616 rs742650 Intron C T 0.00 0.03 0.15 0.06 0.14 0.11
Ch20:59,301,100 rs260741 Intron G A 0.06 0.31 0.24 0.21 0.25 0.27
Ch20:59,305,927 rs260740 Intron T G 0.28 0.25 0.22 0.28 0.22 0.15
Ch20:59,303,025 rs197174 Intron T C 0.63 0.30 0.16 0.26 0.16 0.12
Ch20:59,303,536 rs197173 Intron T G 0.96 0.67 0.72 0.85 0.74 0.74
Ch20:59,309,196 rs6064764 Intron T C 0.03 0.20 0.07 0.32 0.09 0.10
Ch20:59,309,707 rs926632 Intron C T 0.42 0.70 0.85 0.70 0.87 0.89
Ch20:59,319,323 rs882345 Intron A G 0.10 0.16 0.15 0.19 0.13 0.09
Ch20:59,324,630 rs3026575 3’UTR G A 0.00 0.00 0.05 0.00 0.04 0.14
Ch20:59,324,605 rs11570352 3’UTR C T 0.00 0.00 0.05 0.00 0.06 0.06
  1. Fre Alt frequency, UTR untranslated region