Table 1 Overview of measurements in the ACT trial

Quality of life

T0, T3, T6, T15

 Physical functioning

SF-36 PF subscale [72, 73]

 Other subdomains and total

SF-36 [72, 73]

 Renal specific

KDQOL-SF [39]

 General

EQ-5D [69]

 Aerobic capacity

VO₂peak ergometer test [74]

T0, T3, T6, T15

Sub-maximal ergometer test

T0, T3, T6, T15

 Muscle strength

1RM tests for leg extension, leg curl, chest press, close-grip pull-down

T0, T3, T6, T15

 Balance and mobility

Short Physical Performance Battery [41]

T0, T15

 Physical activity level

Baecke questionnaire [42]

T0, T3, T6, T15

Step counter (Yamax SW200) [75]

T0, T3, T6, T15

 Weight, Height, WC, HC

WHO guidelines [76]

T0, T3, T6, T15

 Nutritional status (undernutrition)

SGA [77]

T0, T15

 Body fat percentage

BIA (Biostat Quadscan 4000, Douglas, Isle of Man)

T0, T3, T6, T15

 Muscle mass

BIA (Biostat Quadscan 4000, Douglas, Isle of Man)

T0, T3, T6, T15

24-h creatine excretion [44, 78]

T0, T3, T6, T15

 Blood pressure

(Speidel & Keller Maxi Stabil 3)

T0, T3, T6, T15

 Blood lipids

TG, TC, HDL-C, LDL-C in fasting serum levels (Cholesterol oxidase-phenol aminophenazone method, MEGA AU 510; Merck Diagnostica, Darmstadt, Germany)

T0, T3, T6, T15

 Insulin resistance

HOMA-IR (fasting glucose, insulin)

T0, T3, T15 (all)

 (Postprandial) hyperglycemia

7-point oral glucose tolerance test [47]

T0, T3, T15 (subgroup)

 Medical history

Patient files

T0

 Renal function

eGFR, albuminuria

T0, T3, T6, T15

Medical history

Patients files

T0, T3, T6, T15

 Immunosuppressants

Patient files, plasma drug levels

T0, T3, T6, T15

 Other (e.g anti-hypertensives, anti-diabetics, statins)

Patient files

T0, T3, T6, T15

 Autonomy, competence, relatedness in general

Basic Needs Satisfaction in General Scale (BNSG [48, 49])

T0

 Autonomy, competence, relatedness in exercise

Basic Psychological Needs in Exercise Scale (BPNES [50])*

T3, T6, T15

 Self-regulation of exercise

Behavioral Regulation in Exercise Questionnaire (BREQ-2 [51])

T0, T3, T6, T15

 Self-regulation and autonomy

Treatment Self-Regulation Questionnaire (TSRQ [52])

T3, T6

 Motivation for exercise

Intrinsic Motivation Inventory (IMI [53]) adapted for exercise.

T3, T15

 Motives for exercise

Exercise Motivation Inventory (EMI-2 [54])

T0, T6

 Perceived competence

Perceived Competence Scale (PCS [56, 55])

T3, T6, T15

 Perceived autonomy support

Health Care Climate Questionnaire (HCCQ [55, 57])*

T3, T6, T15

 Fear of movement

Tampa Scale of Kinesiphobia – DV [58]

T0, T3, T15

 Demographics

Date of birth, marital status

T0, T3, T6, T15

Sex, education, ethnicity

T0

 Coping style

Utrecht Coping List [59]

T0

 Nutrition knowledge

Based on questions of national dietary guidelines survey

T0, T15

 Work-induced fatigue

Need for Recovery Scale (NFR [66])

T0, T3, T6, T15

 Chronic fatigue

Dutch Checklist Individual Resilience (CIS-20 [60,61,62])

T0, T3, T6, T15

 Work participation

NIVEL questionnaire [68]

T0, T3, T6, T15

 Self-reported intake

3-day food diary

T0, T3, T6, T15

 Intake biomarkers

24-h excretion of sodium, potassium, urea

T0, T3, T6, T15

Smoking and alcohol consumption

Questionnaire

T0, T6, T15

Process evaluation

Questions about tools, coaches and the program for the patient*

Questions about tools, time/number of visits, and the program for the professional

Focus groups with patients*

Focus group with professionals

T15

 Quality of life

EQ-5D [69]

T0, T3, T6, T15

 Care consumption, intervention costs

Standard Dutch Questionnaire

T0, T3, T6, T9, T12, T15