Table 1 Demographic, laboratory parameters and KDQoL subscales of patients with CKD 3 from C-STRIDE Study
Characteristics | CKD G3a (n = 499) | CKD G3b (n = 778) | Missing value | p-value |
|---|---|---|---|---|
Age (years) | 49.84 ± 12.76 | 52.86 ± 12.71 | 0 | <0.001 |
Men | 355 (71.1%) | 458 (58.8%) | 0 | <0.001 |
Duration of CKD (years) | 1 (0,4) | 1 (0,4) | 0 | 0.45 |
Current smoking | 199 (40.9%) | 313 (41.9%) | 43 | 0.72 |
Drinkers (≥1 times per day) | 15 (3.1%) | 23 (3.1%) | 55 | 0.10 |
High school education (%) | 315 (64.0%) | 398 (51.8%) | 17 | <0.001 |
Body mass index (kg/m2) | 24.71 ± 3.37 | 24.78 ± 4.70 | 102 | 0.74 |
Systolic blood pressure (mmHg) | 129.54 ± 16.67 | 132.01 ± 17.16 | 143 | 0.02 |
Diastolic blood pressure (mmHg) | 82.29 ± 15.56 | 81.65 ± 10.74 | 143 | 0.42 |
Hypertension | 400 (80.2%) | 631 (81.1%) | 0 | 0.68 |
Serum total cholesterol (mmol/L) | 4.89 (4.00,5.97) | 4.68 (3.86,5.79) | 75 | 0.04 |
Serum LDL cholesterol (mmol/L) | 2.67 ± 0.94 | 2.66 ± 1.00 | 97 | 0.82 |
Serum HDL cholesterol (mmol/L) | 1.07 ± 0.31 | 1.13 ± 0.41 | 96 | 0.01 |
Hyperlipidemia | 155 (33.8%) | 214 (29.2%) | 86 | 0.10 |
Serum creatinine (μmol/L) | 129.50 ± 18.84 | 163.27 ± 27.49 | 0 | <0.001 |
eGFR (mL/min/1.73 m2) | 51.61 ± 4.24 | 37.13 ± 4.33 | 0 | <0.001 |
Fasting Blood glucose (mmol/L) | 5.28 ± 1.73 | 5.41 ± 1.86 | 77 | 0.25 |
Diabetes mellitus | 130 (26.1%) | 216 (27.8%) | 0 | 0.50 |
Cardiovascular disease | 128 (25.9%) | 218 (28.5%) | 17 | 0.32 |
Uric acid (μmol/L) | 402.46 ± 105.51 | 426.14 ± 111.37 | 18 | <0.001 |
Hyperuricemia | 256 (52.0%) | 471 (61.4%) | 18 | 0.001 |
Albumin | 39.81 ± 6.96 | 39.56 ± 6.60 | 47 | 0.52 |
ACR (mg/g creatinine) | 315.37 (63.67,724.88) | 340.19 (74.78,860.03) | 175 | 0.19 |
Hematuria | 230 (53.4%) | 332 (50.2%) | 184 | 0.30 |
Hemoglobin | 134.17 ± 21.68 | 127.56 ± 46.83 | 110 | 0.004 |
Anemia | 83 (17.9%) | 185 (26.4%) | 110 | <0.001 |
Serum Bicarbonate | 26.49 ± 4.20 | 25.46 ± 3.83 | 123 | <0.001 |
Metabolic Acidosis | 109 (21.8%) | 180 (23.1%) | 0 | 0.59 |
Serum calcium | 2.24 ± 0.22 | 2.25 ± 0.22 | 49 | 0.71 |
Serum phosphorus | 1.17 ± 0.40 | 1.18 ± 0.25 | 58 | 0.84 |
Serum iPTH | 47.95 ± 28.94 | 59.15 ± 37.74 | 240 | <0.001 |
CKD-MBD | 398 (79.8%) | 636 (81.8%) | 0 | 0.38 |
Hs-CRP | 1.5 (0.66,3.33) | 1.4 (0.59,3.72) | 225 | 0.51 |
Symptoms and Problems (S) | 90.88 ± 11.05 | 89.30 ± 11.52 | 70 | 0.02 |
Effects of the Kidney disease (E) | 88.29 ± 11.94 | 86.49 ± 13.45 | 70 | 0.02 |
Burden of the Kidney disease (B) | 55.86 ± 26.40 | 52.10 ± 27.64 | 70 | 0.02 |
SF-12 Physical Functioning (PCS) | 46.56 ± 8.16 | 44.51 ± 9.22 | 70 | <0.001 |
SF-12 Mental Functioning (MCS) | 51.18 ± 8.38 | 50.2 ± 9.20 | 70 | 0.06 |