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Table 2 Cox regression for in-hospital mortality for AKI and adjusted for age, gender, co-morbidity (Diabetes Mellitus; hypertension; heart failure; vascular disease; malignancy; composite of infection; composite of GI blood loss or hypovolemia) and CRP

From: Hospital acquired Acute Kidney Injury is associated with increased mortality but not increased readmission rates in a UK acute hospital

  Hazard Ratio 95% Confidence Intervals P value
   Lower Upper  
AKI 1.580 1.428 1.747 <0.001
Male gender 1.025 0.951 1.104 0.516
Age (reference [18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35] years)
 Age 36–45 1.941 1.250 3.013 0.003
 Age 46–55 4.097 2.819 5.955 <0.001
 Age 56–65 5.517 3.860 7.887 <0.001
 Age 66–75 8.650 6.110 12.248 <0.001
 Age > 75 16.868 12.028 23.655 <0.001
 Diabetes Mellitus 0.960 0.868 1.062 0.425
 Hypertension 0.741 0.683 0.803 <0.001
 Ischaemic Heart Disease 0.782 0.675 0.906 0.001
 Heart Failure 1.695 1.530 1.879 <0.001
 Vascular Disease 1.512 1.244 1.839 <0.001
 Malignancy 1.884 1.728 2.054 <0.001
 Composite of Infection 0.814 0.741 0.895 <0.001
 Liver Disease 2.612 2.261 3.017 <0.001
 Composite of GI Blood Loss or Hypovolaemia 1.627 1.451 1.823 <0.001
CRP (referenced to CRP < 11)
 Unmeasured 1.217 .904 1.637 0.195
 11–20 2.097 1.577 2.788 <0.001
 21–30 2.223 1.664 2.969 <0.001
 31–40 2.664 2.004 3.542 <0.001
 41–50 2.377 1.763 3.204 <0.001
 51–60 2.237 1.642 3.050 <0.001
 61–70 3.013 2.246 4.043 <0.001
 71–80 2.660 1.976 3.579 <0.001
 81–90 3.220 2.388 4.343 <0.001
 91–100 3.087 2.451 3.889 <0.001
 101–150 3.636 2.872 4.605 <0.001
 151–200 4.026 3.184 5.091 <0.001
 201–250 4.091 3.187 5.251 <0.001
 251–300 4.441 3.441 5.731 <0.001
 301–350 4.254 3.091 5.853 <0.001
 351–400 2.966 2.373 3.707 <0.001
  > 400 5.917 4.464 7.843 <0.001
  1. AKI acute kidney injury, CRP C-reactive protein